Search for dissertations about: "ATF3"

Showing result 1 - 5 of 8 swedish dissertations containing the word ATF3.

  2. 1. End-to-side nerve repair - A study in the forelimb of the rat

    Author : Eleana Bontioti; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nerve regeneration; Kirurgi; traumatology; Surgery; orthopaedics; Medicin människa och djur ; Medicine human and vertebrates ; Retrograde labelling; ATF3; Collateral sprouting; ortopedi; traumatologi; Nerve injury;

    Abstract : Nerve injuries have a profound impact on individuals, suffering for the patients and induce cost for society. When dealing with severe nerve injuries that create a gap between nerve segments or when the injury is at the brachial plexus level, the clinical alternatives are limited. READ MORE

  4. 2. JNK/c-Jun Signaling and Peripheral Nerve Regeneration

    Author : Charlotta Lindwall; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; neuropsykologi; neurofysiologi; neurophysiology; Neurologi; neuropsychology; Neurology; Djurfysiologi; Animal physiology; JNK; signal transduction; nerve regeneration;

    Abstract : The events associated with axonal injury in the peripheral nervous system (PNS) have been described in detail. However, the molecular mechanisms underlying the regenerative response, or neuronal cell death, following axonal injury are poorly understood. READ MORE

  5. 3. Hypospadias : analysis of a complex genetic disorder

    Author : Ana Maria Beleza Meireles; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : BACKGROUND: Hypospadias is a common inborn error of the male urethra that involves an abnormally placed urethral opening. Its complex etiology is largely elusive to date. Twin and familial studies highlight a genetic background in hypospadias. Environmental factors have also been identified, particularly the exposure to endocrine disrupters. READ MORE

  6. 4. Studies of induced transcription in response to an activated Ha-ras, TPA and UV radiation in keratinocytes

    Author : Mats Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : keratinocytes; Ha-ras; ultraviolet radiation; transcription factor; TPA; NF-kB;

    Abstract : The mutational activation of the Ha-ras gene in keratinocytes has been shown to occur during the initiation step in the mouse skin model for multistage carcinogenesis. Skin tumor promoters such as 12-O-tetradecanoylphorbol-13-acetate (TPA) and ultraviolet radiation (UVR) stimulate a selective outgrowth of initiated keratinocytes to form benign tumours (papillomas). READ MORE

  7. 5. Autoantibody profiling in autoimmune diseases

    Author : Shaghayegh Bayati; Peter Nilsson; Elisa Pin; Peter Heeringa; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Autoimmunity; Autoantibodies; Vasculitis; Systemic Sclerosis; affinity proteomics; Biotechnology; Bioteknologi;

    Abstract : Autoimmune disease diagnosis and definition of prognosis can be challenging. Patients with the same autoimmune disease could present with very heterogeneous symptoms. Therefore, there is a need to understand the disease better to improve patients’ diagnosis, and classification, and tailor the treatment. READ MORE