Search for dissertations about: "AU-rich sequence"

Found 4 swedish dissertations containing the words AU-rich sequence.

  2. 1. Control of human papillomavirus type 1 late mRNA stability and translation by an AU-rich RNA element

    Author : Marcus Sokolowski; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; HPV-1; HPV-16; late genes; 3´ UTR; L1; L2; c-fos; AU rich element; HuR; hnRNP C1 C2; mRNA stability; translation; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Abstract : Human Papillomaviruses (HPVs) infect the epithelial tissues in humans and infection with certain high-risk types is associated with cancer. The expressionof the HPV late capsid genes is dependent on cell differentiation. This may be one reason for the lack of HPV replication in vitro. READ MORE

  4. 2. Role of the 3'UTR in translation and stability of HCV and HPV mRNAs

    Author : Lisa Wiklund; Laszlo Szekely; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Hepatitis C virus; Human Papillomavirus; 3’ untranslated region; AU-rich sequence; mRNA stability; translation; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Abstract : Virus mRNAs can be divided into functional regions. The focus of this thesis will be to investigate the function of one of these regions, the 3’ untranslated region (UTR). The 3’UTR of HCV contains a U-rich element and the late 3’UTR of HPV-1 contains an AU-rich element. READ MORE

  5. 3. The role of the RNA-binding protein Wig-1 in post-transcriptional regulation of gene expression

    Author : Cinzia Bersani; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The p53 transcription factor is activated by cellular stress. This triggers transcriptional activation of a number of p53 target genes, leading to responses such as cell cycle arrest and/or induction of apoptosis. Wig-1 is a p53 target gene and its RNA and protein levels increase after p53 protein activation. READ MORE

  6. 4. Posttranscriptional regulation of gene expression in retroviruses and human papillomaviruses

    Author : Wei Tan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : CTE; EIAV; HIV- 1; HPV; Rev; RRE; splice site; SRV- 1; 3 UTR Stockholm 1996 Doctoral Thesis;

    Abstract : Human immunodeficiency virus type I (HIV-1) is the prototype of complex retroviruses, whereas human papillomaviruses (HPVs) are nonenveloped, cricular double-stranded DNA viruses. The HIV-1 Rev protein is a posttranscriptional regulator, which acts on its target RNA sequence termed the Rev-responsive element (RRE) to facilitate nuclear export of unspliced and partially spliced HIV-1 mRNAs, and to improve their stability and translatability. READ MORE