Search for dissertations about: "Ab42"

Showing result 1 - 5 of 6 swedish dissertations containing the word Ab42.

  2. 1. Secondary Nucleation in Amyloid Formation

    Author : Mattias Törnquist; NanoLund: Centre for Nanoscience; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Alzheimer s disease; amyloid; Ab42; aggregation mechanism; aggregation kinetics; secondary nucleation; Protein misfolding;

    Abstract : Research into Alzheimer's disease is still hampered by a lack of fundamental understanding of the underlying mechanisms. While the aggregation of the amyloid β peptide (Aβ) into amyloid fibrils is highly implicated as a key factor in the disease, the molecular nature of its involvement has proven complex and elusive. READ MORE

  4. 2. Big Lessons from Small Bacteria : Following Photo-driven Processes in Photosynthetic Systems with Multidimensional Spectroscopy

    Author : Egle Bukarte; Kemisk fysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Two-dimensional electronic spectroscopy; Ultrafast spectroscopy; Chlorophyll; Bacterial reaction centers; Photosynthetic unit; Purple bacteria; Green bacteria;

    Abstract : Sunlight is a plentiful, continuously flowing source of energy, fuelling life on Earth as we know it. To use this potential, plants, cyanobacteria and photosynthetic bacteria evolved to absorb solar radiance and convert it into a chemically stable form by performing a process known as photosynthesis. READ MORE

  5. 3. Biomarkers in preclinical familial Alzheimer disease

    Author : Steinunn Thordardottir; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Alzheimer disease (AD) is a neurodegenerative disorder, characterized by the accumulation of b-amyloid (Ab) plaques and tangles consisting of hyperphosphorylated tauprotein in the brain. It accounts for 60-70% of dementia cases, making it the most common cause of dementia. READ MORE

  6. 4. Neuroinflammation and its resolution in Alzheimer's disease

    Author : Ying Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Alzheimer's disease (AD) is the most common dementia with high prevalence among an increasing aged population. Despite the existence of symptom-reliving drugs for AD, the clinical trials performed until now have failed to find drugs that cure or stop the progression of AD. New perspectives and strategies for treatments are therefore direly needed. READ MORE

  7. 5. A molecular biological study of Alzheimer's disease : investigation of amyloid precursor protein, amyloid precursor-like protein 2 and presenilin-1

    Author : Janet A Johnston; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The devastating symptoms of Alzheimer's disease result from a progressive regional neurodegenerative process, the cause of which is unknown. Current research suggests that several different mechanisms may be involved, perhaps acting at different points in a common pathological pathway. READ MORE