Search for dissertations about: "Absorption Concentration profile"

Showing result 11 - 14 of 14 swedish dissertations containing the words Absorption Concentration profile.

  2. 11. Furosemide dosage input : consequences for diuretic effect, tolerance and efficiency

    Author : Monique Wakelkamp; Karolinska Institutet; Karolinska Institutet; []
    Keywords : furosemide; drug input rate; pharmacokinetics; pharmacodynamics; tolerance; efficiency; probenecid;

    Abstract : The development of new dosage forms raises the question of how the pharmacokinetic pharmacodynamic (PK-PD) profile of a drug is influenced by the drug input rate. Furosemide was used as a model drug to study the relationship between drug input rate and effect. READ MORE

  4. 12. Effect of local food on lumefantrine bioavailability and population pharmacokinetics in Ugandan children with malaria

    Author : Norah Mwebaza; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background. Artemether-lumefantrine (AL) is widely adopted as first-line treatment for uncomplicated malaria. Lumefantrine (LUM), the long acting partner drug is critical for cure by eliminating malaria parasites left after artemether exposure. READ MORE

  5. 13. Fermentation of quinoa, canihua and amaranth to degrade phytate and improve mineral bioavailability

    Author : Vanesa Castro-Alba; Avdelningen för livsmedel och läkemedel; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Quinoa; Canihua; Amaranth; Iron; Zinc; Calcium; Phytate; Fermentation; Accessibility; Bioavailability;

    Abstract : Plant-based diets are the main source of nutrients for vegetarians worldwide and for low-income inhabitants of developing countries, such as in rural areas of Bolivia. These diets may contain high levels of mineral inhibitors such as phytate that impairs mineral absorption in the human gut. READ MORE

  6. 14. Probiotics and berry-associated polyphenols: catabolism and antioxidative effects

    Author : Maja Jakesevic; Avdelningen för livsmedel och läkemedel; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bilberry; Rosehips; Chokeberry; Probiotics; Lactic acid bacteria; Polyphenols; Ischemia-reperfusion; Oxidative stress;

    Abstract : Oxidative stress can cause damage to DNA, proteins and lipids and is associated with inflammation and various human diseases as cancer, atherosclerosis, and autoimmune diseases. Polyphenol-rich diet, such as fruits and berries, may act as antioxidants and prevent oxidative stress and, thereby, associated diseases. READ MORE