Search for dissertations about: "Accumbens nucleus"
Showing result 1 - 5 of 66 swedish dissertations containing the words Accumbens nucleus.
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1. Motion and Emotion : Functional In Vivo Analyses of the Mouse Basal Ganglia
Abstract : A major challenge in the field of neuroscience is to link behavior with specific neuronal circuitries and cellular events. One way of facing this challenge is to identify unique cellular markers and thus have the ability to, through various mouse genetics tools, mimic, manipulate and control various aspects of neuronal activity to decipher their correlation to behavior. READ MORE
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2. Nicotine sensitization and the effects of extended withdrawal - behavioral, neurochemical and electrophysiological studies in the rat
Abstract : Tobacco use is one of the primary factors for global burden of disease and often results in life-long nicotine addiction, only a small percentage users are able to maintain cessation. The life-long addiction together with a high relapse risk might be connected to drug-induced altered neural circuits. READ MORE
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3. Taurine and dopamine-related effects of ethanol. An experimental study in rodents
Abstract : The reinforcing properties of alcohol (ethanol) are associated with activation of the mesolimbic dopamine system and the concomitant increase in dopamine in the nucleus accumbens (nAc). Changes in this system are thought to be a predominant underlying factor in promoting excessive alcohol intake and alcohol use disorder. READ MORE
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4. Glycine receptors in the central nervous system - development, distribution and relation to actions of alcohol
Abstract : The widespread consumption of alcohol and the great socioeconomic impact of alcohol abuse and addiction have contributed to the extensive investigations of this substance. Despite great efforts there is still uncertainty concerning how alcohol exerts its effects and the mechanisms behind the transition from consumption to addiction. READ MORE
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5. Preclinical investigations of GlyT-1 inhibition as a new concept for treatment of alcohol dependence
Abstract : Alcohol addiction and abuse is a main contributor to the global burden of disease and is a high public health priority. Alcohol addiction is a chronically relapsing neurobiological disorder affecting multiple neurotransmitter systems. READ MORE