Search for dissertations about: "Acetylcholine esterase"

Showing result 6 - 10 of 11 swedish dissertations containing the words Acetylcholine esterase.

  2. 6. Targeting Biological Systems by Organic Synthesis Methods - Cancer Cells and Proteins

    Author : Cecilia Winander; Lars Baltzer; Stefan Sjöberg; Jörgen Carlsson; Vladimir Tolmachev; Thomas Schrader; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; carborane; doxorubicin; 125I; molecular recognition; four-helix bundle; polypeptide conjugate; affinity; chitinase; acetylcholine esterase; Organisk kemi;

    Abstract : This thesis describes the design and synthesis of molecules with potential roles in biomedicine, with an emphasis on molecular recognition in complex biological environments. The first chapter describes the synthesis and evaluation of compounds for use in nuclide therapy. READ MORE

  4. 7. Improved environmental monitoring and assessment : Establishing links between effects of chemical pollution at different levels of biological organization in a Baltic Sea bioindicator species (Monoporeia affinis)

    Author : Martin Reutgard; Magnus Breitholtz; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Environmental health assessment; environmental monitoring; chemical pollution; hypoxia; bioindicators; biomarkers; teratogenicity; embryo toxicity; oxidative stress; acetylcholine esterase. Monoporeia affinis; Baltic Sea; Applied Environmental Science; tillämpad miljövetenskap;

    Abstract : A large number of chemicals enters the marine environment via atmospheric deposition, run-off, rivers and streams, industrial effluents and municipal wastewater. To understand how chemicals affect environmental health, monitoring and assessment approaches need to combine physical, chemical and biological effect parameters from different levels of biological organization. READ MORE

  5. 8. Novel pharmacological treatment alternatives for schizophrenia

    Author : Charlotte Wiker; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Antipsychotic drugs are commonly divided into typical (first generation) and atypical (second generation) antipsychotic drugs. Clinically effective doses of typical antipsychotic drugs generate a striatal dopamine D2 receptor occupancy of about 70 80%, approaching a level that is associated with a high risk of extrapyramidal side effects. READ MORE

  6. 9. MuSK Antibody(+) Versus AChR Antibody(+) Myasthenia Gravis : Clinical, Neurophysiological and Morphological Aspects

    Author : Anna Rostedt Punga; Erik Stålberg; Hannu Kalimo; John Newsom-Davis; Uppsala universitet; []
    Keywords : Neurosciences; myasthenia gravis; MuSK antibody; AChR antibody; myopathy; single-fiber EMG; mitochondria; Swedish MG questionnaire; quality of life; Neurovetenskap;

    Abstract : Myasthenia gravis (MG) is an autoimmune neuromuscular disorder that causes fluctuating muscle weakness. MG may be divided into an ocular form and a generalized form based on the involved muscles. Treatment differs between these different MG forms. READ MORE

  7. 10. On the actions of neurotrophic factors on the chromaffin cells of the adrenal medulla

    Author : Petter Förander; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Neural crest; chromaffin cells; neurotrophic factors; NGF; NT-3; NT4; CNTF; GDNF; TGFß; FGF2; glucocorticoids; Intra oculartransplantation ; primary cultures; neurite outgrowth;

    Abstract : Chromaffin cells producing adrenaline or noradrenaline are the predominant cell type in the adrenal medulla, but ganglion cells and Schwann cells are also present. All cells of the adrenal medulla are derived from the neural crest, which is a transient neuroectoderm-derived embryonic structure. READ MORE