Search for dissertations about: "Acute Lymphoblastic Leukemia ALL"

Showing result 6 - 10 of 72 swedish dissertations containing the words Acute Lymphoblastic Leukemia ALL.

  2. 6. Gene Expression and DNA Methylation in Acute Lymphoblastic Leukemia

    Author : Jessica Nordlund; Syvänen Ann-Christine; Xavier Estivill; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Digital gene expression; Allele-specific gene expression; DNA methylation; Epigenetics; Acute lymphoblastic leukemia; Molekylär medicin; Molecular Medicine;

    Abstract : Pediatric acute lymphoblastic leukemia (ALL) is the most common malignancy in children, which results from the malignant transformation of progenitor cells in the bone marrow into leukemic cells. The precise mechanisms for this transformation are not well defined, however recent studies suggest that aberrant regulation of gene expression or DNA methylation may play an important role. READ MORE

  4. 7. Unwinding the layers of high hyperdiploid childhood acute lymphoblastic leukemia

    Author : Larissa Helena Moura-Castro; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; acute lymphoblastic leukaemia ALL ; high hyperdiploid ALL; chromatin structure; transcriptional regulation; CTCF; cohesin; clonal heterogeneity;

    Abstract : .... READ MORE

  5. 8. Registry-Based Studies in Adult Acute Lymphoblastic Leukemia in Sweden : Survival and Quality of Life

    Author : Emma Bergfelt Lennmyr; Helene Hallböök; Martin Höglund; Jan Maxwell Nørgaard; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute Lymphoblastic Leukemia; Philadelphia Chromosome; Overall Survival; Population-based; Quality Registry; Relapse; Patient-Reported Outcome; Health-Related Quality of Life; Depression;

    Abstract : Acute lymphoblastic leukemia (ALL), a common child malignancy, also constitutes a minor fraction of adult cancer with approximately 50 new cases per year in Sweden. While the five-year overall survival (OS) in pediatric ALL is more than 90%, the prognosis in adults is dismal. READ MORE

  6. 9. Prognostic factors, treatment and outcome in adult acute lymphoblastic leukemia : Population-based studies in Sweden

    Author : Piotr Kozlowski; Helene Hallböök; Maria Åström; Anita W. Rijneveld; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute Lymphoblastic Leukemia; adult; chemotherapy; prognosis; population-based; Onkologi; Oncology;

    Abstract : Acute lymphoblastic leukemia (ALL) has poor prognosis in older/elderly adults and in high-risk/relapsed disease. Recommended treatment of ALL was evaluated (study I-IV). Data was obtained from the Swedish Acute Leukemia registries and from patient records.I. READ MORE

  7. 10. Genetic studies of acute lymphoblastic leukemia

    Author : Ekaterina Kuchinskaya; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy, comprising approximately 25% of all childhood cancers. A huge improvement in outcome of children with ALL during the last 20 years has resulted in remission rates exceeding 95% and a 5 year event-free-survival approaching 80%. READ MORE