Search for dissertations about: "Acute and long-term DRG cultures"

Found 2 swedish dissertations containing the words Acute and long-term DRG cultures.

2. 1. Histochemical, biochemical and electrophysiological studies on dorsal root ganglion cultures : focusing on galanin, neuropeptide Y and glutamate

   Author : Nora Kerekes; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Acute and long-term DRG cultures; aFGF; BDNF; bFGF; bradykinin; excitability; galanin; glutamate; leukemia inhibitory factor; neuropeptide Y; : NGF; regeneration; whole cell patch clamp.;

   Abstract : Galanin (Gal) and neuropeptide Y (NPY) are two peptides, which are strongly up- regulated in a population of dorsal root ganglion (DRG) neurons after peripheral nerve injury (axotomy). Both peptides may be involved in the control of pain sensation, especially after nerve injury (neuropathic pain). READ MORE

4. 2. Modulation of pain by immune factors : a study on interferon-g and its receptor in nociceptive transmission

   Author : Kristina S Vikman; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Cytokines; interferon-gamma; dorsal horn; hypersensitivity; nociceptive transmission; pain; GluR1; AMPA receptor; disinhibition; spontaneous activity; primary cell culture; two-compartment model; spinal cord.;

   Abstract : Immune cytokines have been implicated as important neuromodulators, contributing to neuronal plasticity both in the adult and developing nervous system. In addition, they have been assigned a potential role in the generation of pathological pain, which may occur as a severe symptom following disease states in the nervous system. READ MORE