Search for dissertations about: "Adaptive response"

Showing result 1 - 5 of 460 swedish dissertations containing the words Adaptive response.

  1. 1. Resilience in High Risk Work : Analysing Adaptive Performance

    Author : Amy Rankin; Henrik Eriksson; Margareta Lützhöft; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Resilience Engineering; Safety Management; Adaptive Capacity; Improvisation;

    Abstract : In today’s complexsocio-technical systems it is not possible to foresee and prepare for allfuture events. To cope with the intricacy and coupling between people,technical systems and the dynamic environment people are required tocontinuously adapt. READ MORE

  2. 2. Optimal (Adaptive) Design and Estimation Performance in Pharmacometric Modelling

    Author : Alan Maloney; Ulrika Simonsson; Mats Karlsson; Andy Grieve; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Phase II; dose response; optimal design; adaptive design; exposure response; count data;

    Abstract : The pharmaceutical industry now recognises the importance of the newly defined discipline of pharmacometrics. Pharmacometrics uses mathematical models to describe and then predict the performance of new drugs in clinical development. READ MORE

  3. 3. Optimal adaptive designs and adaptive randomization techniques for clinical trials

    Author : Yevgen Ryeznik; Warwick Tucker; Andrew Hooker; Franz König; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; optimal designs; optimal adaptive designs; randomization in clinical trials; restricted randomization; adaptive randomization; unequal cost; allocation ratio preserving randomization procedures; heterogeneous costs; multi-arm clinical trials; randomization-based inference; unequal allocation; Tillämpad matematik och statistik; Applied Mathematics and Statistics;

    Abstract : In this Ph.D. thesis, we investigate how to optimize the design of clinical trials by constructing optimal adaptive designs, and how to implement the design by adaptive randomization. READ MORE

  4. 4. Effects of Complement Opsonization of HIV on Dendritic Cells : and Implications for the Immune Response

    Author : Rada Ellegård; Marie Larsson; Jorma Hinkula; Johan D Söderholm; William Paxton; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; HIV; dendritic cells; complement; innate immune response; TLR signaling; T cell activation; NK cells; inflammation; antiviral response; immune evasion;

    Abstract : Dendritic cells are key players during HIV pathogenesis, and shape both the immediate immune response at the site of infection as well as directing the adaptive immune response against the virus. HIV has developed a plethora of immune evasion mechanisms that hijack dendritic cell functions, suppressing their ability to mount an accurate immune response and exploiting them for efficient viral transfer to target T cells. READ MORE

  5. 5. Robust analysis of delaminating composites using adaptive isogeometric shell elements

    Author : Elias Börjesson; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; path-following solver; delamination; adaptive; Isogeometric analysis;

    Abstract : Fibre reinforced composites are considered to be one of the material categories that offer the best possibilities to create efficient lightweight designs. Many companies in the transport sector therefore work towards increasing the amount of fibre composites in their products, in an attempt to lower the fuel consumption of their vehicles. READ MORE