Search for dissertations about: "Adhesions"

Showing result 16 - 20 of 54 swedish dissertations containing the word Adhesions.

  2. 16. Collagen-binding integrin α2β1 activity in vivo and in vitro : Effects of platelet-derived growth factor-BB

    Author : Karina Åhlén; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Integrin α2β1; PDGF-BB; fibroblast; interstitial fluid pressure; cytoskeletal interaction; phosphatidylinositol 3-kinase; [Ca2 ]i; Biokemi; Biochemistry; Biokemi; Medical and Physiological Chemistry; medicinsk och fysiologisk kemi;

    Abstract : The expression of integrins by two cell clones from a rat colon carcinoma was investigated. Cloned cells that gave rise to regressive tumors, but not cells that gave rise to progressive, lethal, tumors, adhered to interstitial collagens through the integrin α2β1, although both cell types expressed it. READ MORE

  4. 17. Experimental Models of the Human Peritoneal Environment: Effects of TGF-beta and Hyaluronan

    Author : Peter Falk; Göteborgs universitet; []
    Keywords : Adhesion formation; experimental model; cell culture; mesothelial cells; peritoneum; fibrinolytic system; transforming growth factor beta; hyaluronan; proliferation;

    Abstract : BACKGROUND Post surgical adhesion formation is still an unsolved problem and occurs when there is an imbalance between fibrin deposition and fibrin clearing capacity in the abdominal cavity. Transforming growth factor beta (TGF-?) is associated with fibrosis and hyaluronan has in several studies been showed to reduce adhesions. READ MORE

  5. 18. Molecular Mechanisms of Action of Histidine-rich Glycoprotein in Angiogenesis Inhibition

    Author : Chunsik Lee; Lena Claesson-Welsh; Jan Palmblad; Uppsala universitet; []
    Keywords : Cell and molecular biology; anti-angiogenesis; angiogenesis inhibitor; endothelial cell; histidine-rich glycoprotein; focal adhesion; tumor-associated macrophages; VEGF; MMP; Cell- och molekylärbiologi;

    Abstract : Angiogenesis, de novo synthesis of blood vessels from the pre-existing vasculature, is required both during embryonic development and in pathophysiological conditions. In particular, tumor growth needs new capillary vessels in order to both deliver oxygen and nutrients and to remove toxin and metabolites. READ MORE

  6. 19. Phalangeal fractures : current treatments, complications and innovations

    Author : Johanna von Kieseritzky; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Phalangeal fractures are common and most of them heal well without surgical intervention. However, the comminuted and displaced unstable fractures sometimes require surgery. There are many different surgical options available such as K-wires, screws of different kinds, plates and screws, and external fixations. READ MORE

  7. 20. Anaemia, blood loss and colorectal cancer

    Author : Malin Mörner; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Introduction: Colorectal cancer (CRC) is the fourth most common cancer worldwide and strikes both sexes. The age-adjusted 5-year survival in Sweden was 60% in the early 21 st century. Approximately 50% of patients are anaemic at the time of diagnosis. Many patients need blood transfusion due to anaemia or surgical blood-loss. READ MORE