Search for dissertations about: "Adhesive particle mixing"

Found 4 swedish dissertations containing the words Adhesive particle mixing.

  2. 1. A Multi-Scale Approach To Adhesive Mixing

    Author : Duy Nguyen; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Adhesive particle mixing; CFD simulation; multiscale; dry particle coating; regime map.; DEM simulation; dry powders for inhalation;

    Abstract : Adhesive particle mixing is a fundamental process in many applications, especially in dry powders for inhalation. Despite its importance, a mechanistic process description for designing the structure of interest is still lacking. READ MORE

  4. 2. Mechanisms of adhesive mixing for drug particle inhalation (Numerical investigation of the interplay between formulation variables)

    Author : Mohammadreza Tamadondar; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Discrete Element Method; Agglomerate; Carrier Particle; Adhesive mixing; Dispersion; DPI-formulation;

    Abstract : Formulation of therapeutic dry powders for lung drug delivery via inhalation is done via adhesive mixing. In this process, micron-sized active pharmaceutical ingredient particles are blended with relatively coarse carrier particles until stable adhesive units of carrier and drug particles are formed. READ MORE

  5. 3. Understanding Adhesive Mixtures for Inhalation : Particle Dynamics Modelling and Segregation Experiments

    Author : Sohan Sarangi; Göran Frenning; Göran Alderborn; Kyrre Thalberg; Johannes Khinast; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inhalation; adhesive mixtures; dry powder inhaler; discrete element method; segregation; stability; modeling; Galenisk farmaci; Pharmaceutics; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Pulmonary route has been used as a source of drug delivery to lungs for centuries. Drugformulation decides the type of inhaler devices such as pressurized metered-dose inhalers(pMDIs), nebulizers and dry powder inhalers (DPIs). READ MORE

  6. 4. Large organic aerosols in a human exposure chamber : applications in occupational dermatology and lung medicine

    Author : Lennart Lundgren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Aerosol; bakery dust; bronchoalveolar lavage; chamber design; dermal exposure; exposure chamber; inhalation; large organic aerosols; mannequin; neutralizer; particle size; pinewood dust; skin;

    Abstract : Exposure to large organic aerosol particles may cause respiratory and skin reactions. The use of human exposure chambers offers possibilities for experimental exposure challenges carried out with patients, in research and for investigations of the effects of exposure on the skin and in the respiratory tract. READ MORE