Search for dissertations about: "Adrenal tumour"

Showing result 1 - 5 of 11 swedish dissertations containing the words Adrenal tumour.

2. 1. Clinical aspects of Adrenalectomy

   Author : Lo Hallin Thompson; Lund Kirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adrenalectomy; Adrenal tumour; Adrenal surgery; Adrenal incidentaloma; Health Related Quality of Life; Quality register;

   Abstract : Annual rates of adrenalectomy have doubled in the last 20 years as a consequence of increased detection of adrenal incidentalomas, improved biochemical diagnosis, genetic screening, and minimally invasive surgical techniques. Most adrenal incidentalomas are benign non-functional adrenocortical adenomas. READ MORE

4. 2. Incidentally discovered adrenal tumours, adrenal metastases and pheochromocytomas - Clinical and epidemiological aspects

   Author : Andreas Muth; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Incidental Findings; Adrenal incidentaloma; Adrenal Gland Neoplasms; Adrenalectomy; Follow-Up Studies; Quality of Life; Pheochromocytoma epidemiology; Pheochromocytoma genetics; Paraganglioma epidemiology; Paraganglioma genetics;

   Abstract : With increasing use of high resolution radiological imaging incidentally discovered adrenal tumours (adrenal incidentalomas, AI) have become a common clinical problem. The aim of work-up and follow-up of patients with AI is to detect malignant (primary or metastatic) and/or hormone-producing tumours. READ MORE

5. 3. Vesicle proteins as markers for neuroendocrine tumors

   Author : Anne-Marie Levin Jakobsen; Göteborgs universitet; []
   Keywords : Neuroendocrine tumours; gastrointestinal tract; pancreas; adrenal; vesicle proteins; ; SV2; NESP55; VMAT1; VMAT2; MIBG;

   Abstract : The neuroendocrine (NE) tumours comprise a diversity of tumours which share commonproperties, e.g. the capacity to produce, store and release hormones. A prominent feature ofthe NE phenotype is the production of secretory granules with associated vescicle proteins,e. READ MORE

6. 4. New Insights in Adrenal Tumourigenesis

   Author : Rajani Maharjan; Peyman Björklund; Michaela Luconi; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cortisol producing adenomas; adrenocortical carcinomas; mutation; heterogeneity; PRKACA; TERT; CTNNB1; Molekylär genetik; Molecular Genetics;

   Abstract : Unilateral cortisol producing adenoma (CPA) is the most common cause of ACTH-independent Cushing’s syndrome and is surgically curable. On the other hand, adrenocortical carcinomas (ACCs) are rare and aggressive tumours. READ MORE

7. 5. Adrenal Bioactivation and Toxicity of 3-MeSO2-DDE, o,p´-DDD and DMBA Investigated in Tissue Slice Culture

   Author : Örjan Lindhe; Jan Alexander; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; adrenal cortex; 3-MeSO2-DDE; o; p´-DDD; DMBA; bioactivation; binding; toxic; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Ecotoxicology; ekotoxikologi;

   Abstract : I developed a precision-cut adrenal slice culture procedure to investigate cytochrome P450 (CYP) catalysed irreversible binding and adrenocorticolytic effects in human, rodent, and fish adrenal tissue, ex vivo. Autoradiography and radioluminography of exposed tissue slices showed that the potent adrenal toxicant 3-methylsulphonyl-2,2´-bis(4-chlorophenyl)-1,1´-dichloroethene (MeSO2-DDE) causes a selective metabolite binding in zona fasciculata (ZF), which is diminished by the CYP11B1 inhibitor metyrapone. READ MORE