Search for dissertations about: "Adult neural stem cell"

Showing result 1 - 5 of 101 swedish dissertations containing the words Adult neural stem cell.

2. 1. Modeling Neural Stem Cell and Glioma Biology

   Author : Tobias Bergström; Karin Forsberg-Nilsson; Staffan Johansson; Sven Påhlman; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neural stem cell; integrins; glioma; PDGF; mast cell; Molekylär cellbiologi; Molecular Cellbiology; Oncology; Onkologi;

   Abstract : This thesis is focused on neural stem cell (NSC) and glioma biology. I discuss how NSCs interact with extracellular matrix (ECM) proteins in the stem cell niche, and investigate the consequences of deregulated Platelet-derived growth factor (PDGF) signaling for embryonic NSCs in transgenic mice. READ MORE

4. 2. Neural stam cells, TLX, and Neuroblastoma

   Author : Ravi Kanth Rao Saini; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma; TLX; Neural Stem Cells; Dedifferentiation; DISC-1; DNA-PKcs;

   Abstract : Neuroblastoma (NB) is one of the most commonly diagnosed extracranial tumors in children below five years of age. Moreover, NB accounts for almost 12-15% of all childhood cancer related fatalities. To date, the origin of NB has been linked to the neural crest derived sympathoadrenal progenitor cells. READ MORE

5. 3. Adult Neural Stem Cells-Influence of Stroke, Inflammation and Aging

   Author : Henrik Ahlenius; Lund Neurologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammation; Neural stem cells; adult; neurogenesis; stroke; aging; TNF-R1; TNF-α;

   Abstract : Neural stem cells (NSCs) in the embryo generate neurons, astrocytes and oligodendrocytes, the principal cells of the central nervous system (CNS), which contribute to the full diversity of the brain. Some NSCs persist in the adult brain and ensures neurogenesis throughout adult life in the subventricular zone (SVZ) and the subgranular zone (SGZ). READ MORE

6. 4. Neural Stem and Progenitor Cells : Cellular Responses to Known and Novel Factors

   Author : Jimmy Larsson; Karin Forsberg-Nilsson; Ola Hermanson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neural stem cell; differentiation; proliferation; migration; PDGF; SCF; NRBP2; medulloblastoma; Biochemistry; Biokemi; Medical Biochemistry; Medicinsk biokemi;

   Abstract : Neural stem cell self-renewal and differentiation are tightly regulated events during CNS development, leading to cell division into new neural stem cells or the formation of neurons and glial cells. This thesis focuses on the cellular responses induced by known and novel factors in neural stem and progenitor cells (NSPCs). READ MORE

7. 5. Adult neural stem cells in neuroinflammation

   Author : Ruxandra Covacu; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Neural stem cells; inflammation; EAE; NO; neurogenesis; HMGB1; TLR; TNFalpha;

   Abstract : Adult neural stem cells (NSC) can be isolated from the subventricular zone (SVZ) of the lateral ventricles, the subgranular zone (SGZ) of the hippocampus and the central canal of the spinal cord. These cells are thought to have regenerative potential and pose important therapeutic possibilities in neuroinflammatory conditions such as Multiple Sclerosis (MS). READ MORE