Search for dissertations about: "Adverse drug effect chemotherapy"
Showing result 1 - 5 of 7 swedish dissertations containing the words Adverse drug effect chemotherapy.
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1. The proteasome as a target for cancer therapy
Abstract : The main objective of this PhD thesis was to evaluate the significance of proteasome genes as prognostic markers for different cancer types and identify specific cancer forms that respond to proteasome inhibition. The proteasome (PSM) plays an important role in maintaining cellular proteostasis and degrades the majority of proteins that require breakdown in the cell. READ MORE
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2. Bacterial toxins for cancer treatment
Abstract : Even though anti‐cancer chemotherapy has been continuously improved during the last decades. problems with adverse effects and drug resistance still constitutes a considerable obstacle and sets a demand for new effective treatment options. READ MORE
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3. Novel combination chemotherapy for treatment and control of schistosomiasis among school children
Abstract : Despite reported success in reducing severe disease-associated morbidities in endemic countries, praziquantel (PZQ) alone has failed to control and eliminate schistosomiasis, partly due to its poor efficacy against immature/juvenile worms. Artemisinin derivatives are efficacious against juvenile schistosomes. READ MORE
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4. Pharmacovigilance of preventive chemotherapy for the control of schistosomiasis and soil-transmitted helminths in Ethiopia
Abstract : The World Health Organization (WHO) recommends preventive chemotherapy (PC) as a core public health intervention for the control and elimination of schistosomiasis and soil transmitted helminths (STHs) in endemic countries. Despite being amenable to available treatments and ongoing PC, schistosomiasis and STHs remain causes of significant morbidity and associated complications in endemic areas. READ MORE
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5. Mechanistic study of antiangiogenic agents in cancer therapy
Abstract : Tumor growth and metastasis are dependent on angiogenesis that constantly alters the tumor microenvironment. Based on the antiangiogenic principle proposed more than 40 years ago by Dr. READ MORE