Search for dissertations about: "Agonist"

Showing result 1 - 5 of 434 swedish dissertations containing the word Agonist.

  2. 1. Galanin receptor ligands

    Author : Johan Runesson; Ülo Langel; Lena Mäler; Stockholms universitet; []
    Keywords : Galanin; GALP; GPCR; Agonist; GalR; Chimeric peptide; Inositol phosphate production; Receptor specificity; Neurochemistry and Molecular Neurobiology; neurokemi med molekylär neurobiologi;

    Abstract : In the nervous system galanin primarily displays a modulatory role. The galaninergic system consists of a number of bioactive peptides with a highly plastic expression pattern and three different receptors. The lack of receptor subtype selective ligands and antibodies have severely hampered the charac-terization of this system. READ MORE

  4. 2. Clozapine as a dopamine D₁ receptor agonist

    Author : Peter Salmi; Leif Lindström; Stockholms universitet; []
    Keywords : psykologi; Psychology;

    Abstract : Objectives'. The present study had two major objectives; [1] to examine the specific role of dopamine D, and DM receptors in body temperature regulation in rats, and [2] to examine in vivo dopamine D, and Dm receptor agonist/antagonist properties of clozapine by use of core temperature measurements.Methods'. READ MORE

  5. 3. Pre-clinical investigations of a dopamine autoreceptor agonist : selective stimulators of central dopamine and serotonin receptors

    Author : Seth-Olov Thorberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Abstract : .... READ MORE

  6. 4. Selectivity of dopamine D1 and D2 receptor agonists – A combined computational approach

    Author : Marcus Malo; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; dopamine; agonists; GPCRs; pharmacophore modeling; protein structure modeling; agonist selectivity;

    Abstract : Dopamine (DA) is an endogenous neurotransmitter acting in the central nervous system. DA plays a key role in many vital brain functions such as behavior, cognition, motor activity, learning, and reward. Dopamine receptors belong to the rhodopsin like family of G-protein coupled receptors (GPCRs). READ MORE

  7. 5. Premenstrual dysphoric disorder in relation to neuroactive steroids and alcohol

    Author : Sigrid Nyberg; Britth-Marie Landgren; Umeå universitet; []
    Keywords : premenstrual dysphoric disorder; GnRH-agonist; progesterone; allopregnanolone; alcohol; saccadic eye velocity; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Introduction: Premenstrual Dysphoric Disorder (PMDD) is a condition that affects about 2-6% of women of reproductive age. The relation to ovarian steroids is apparent as symptoms are absent during anovulatory cycles. READ MORE