Search for dissertations about: "AhR"

Showing result 1 - 5 of 73 swedish dissertations containing the word AhR.

  2. 1. Chemical mixtures and interactions with detoxification mechanisms and biomarker responses in fish

    Author : Johanna Gräns; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Fish; AhR; CYP1A; PXR; Chemical mixtures; Chemical interaction; Biomarker;

    Abstract : Several classes of anthropogenic chemicals are present as mixtures in the aquatic environment. However, information of how wildlife species, including fish, are affected by exposures to chemical mixtures is limited. READ MORE

  4. 2. ENVIRONMENTAL CONTAMINANTS AND SPERM Y:X CHROMOSOME RATIO. Impact of androgen- and dioxin-related effects in vivo and in vitro

    Author : Tarmo Tiido; Malmö Reproduktionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AR; polymorphisms; Sertoli cell; endocrine disruption; inhibitory cross-talk; Biomedicinska vetenskaper; Biomedical sciences; AHR; sperm Y:X chromosome ratio; sex ratio; POPs; TCDD;

    Abstract : During the last decades, there has been concern that the environmental contaminants, such as POPs, may contribute to sex ratio changes in offspring of exposed populations. Accidental exposure to TCDD has been shown to be associated with fewer sons in men who were exposed in adolescence or earlier in life. READ MORE

  5. 3. The Threat to the Baltic Salmon - a Combination of Persistent Pollutants, Parasite and Oxidative Stress

    Author : Maria Persson; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Salmo salar; Atlantic salmon; polychlorinated biphenyls; Animal ecology; akvatisk ekologi; limnologi; Marinbiologi; limnology; aquatic ecology; marine biology; Hydrobiology; Ekologi; Ecology; lake Vänern; lake Vättern; Baltic Sea; Eubothrium crassum; aryl hydrocarbon receptor; AHR; consumption advice; stable isotopes; astaxanthin; EROD; M74; antioxidants; biomagnification; cestodes; parasites; DDT; Djurekologi; Environmental chemistry; Miljökemi; PCB;

    Abstract : Atlantic salmon (Salmo salar) from the Baltic Sea suffer from a reproduction disease known as the M74-syndrome. Newly hatched fry develop nerve disorders and die between 3-5 days after the first symptoms are seen. This is a maternally transmitted disease that is casued by a thiamine (vitamin B1) deficiency. READ MORE

  6. 4. Chemical and bioanalytical characterisation of PAH-contaminated soils : identification, availability and mixture toxicity of AhR agonists

    Author : Maria Larsson; Magnus Engwall; Jessika Hagberg; Peter Haglund; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Polycyclic aromatic compounds; Soil; Risk assessment; Mixture studies; AhR-mediated activity; REPs; GC MS; H4IIE-luc bioassay; Chemistry; Kemi;

    Abstract : Contaminated soils are a worldwide problem. Polycyclic aromatic hydrocarbons (PAHs) are common contaminants in soil at former industrial areas, especially at old gasworks sites, gas stations and former wood impregnation facilities. READ MORE

  7. 5. Evolution and Ecology of AhR genes in Atlantic salmon (Salmo salar L.)

    Author : Maria Hansson; Biodiversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; AhR genes; Atlantic salmon; gene evolution; phylogenetics; environmental pollutants; Baltic Sea; ecotoxicology; Animal ecology; Djurekologi;

    Abstract : In vertebrates, studies of the aryl hydrocarbon receptor (AhR) have been of particular interest due to its direct involvement in the toxic effects exerted by several environmental pollutants, such as PCB and dioxin. After binding to the toxic molecule, this receptor initiates transcription of several genes that are part of the biotransformation battery but most notably the cytochrome P450 (CYP) genes, which results in an excessive release of oxidative enzymes and free radicals. READ MORE