Search for dissertations about: "Akt PKB"

Showing result 11 - 15 of 22 swedish dissertations containing the words Akt PKB.

  2. 11. Protease proforms as hematopoietic regulators

    Author : Stefan Sköld; Avdelningen för hematologi och transfusionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; granulopoiesis proform PR3 NO ribonucleotide reductase; extracellular fluids; Haematology; Hematologi; extracellulära vätskor;

    Abstract : A common feature in myeloid leukemia is suppression of normal hematopoiesis, leading to infections, bleeding and anemia. It has been suggested for a long time that leukemic cells possess a growth-advantage by overproducing an inhibitor - a leukamia associated inhibitor. READ MORE

  4. 12. Aspects of interferon alpha signalling in hematopoetic cells

    Author : Lennart Carlsson; erik lundgren; Ulrich Kalinke; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; interferon; human; B-lymphocyte; survival; proliferation; myeloma; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : The type I interferons (IFN) are a family of cytokines with pleiothropic activities that include inhibition of viral replication, cell proliferation and activation of the immune system. These properties give the IFNs important physiological and pathological roles in infection and cancer and have led to their therapeutic use for many clinical conditions. READ MORE

  5. 13. Angiogenic growth factors : mechanism of action and function in vascular development

    Author : Charlotte Rolny; Andrius Kazlauskas; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; PDGF-BB; VEGF; angiogenesis; hypoxia; migration; heparin; Molekylärmedicin; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Molecular Medicine; molekylär medicin genetik och patologi ;

    Abstract : The mature vascular system is composed of a network of blood vessels organized into arteries, capillaries, and veins. The vessels are composed of endothelial cells surrounded by smooth muscle cells and embedded in a specialized basement membrane. READ MORE

  6. 14. Proinsulin C-peptide : membrane interactions and intracellular signaling

    Author : Zhihui Zhong; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Human renal tubular cell; intracellular signal transduction; ERK1 2; JNK; Na ; K -A TPase; G-protein coupled receptor.;

    Abstract : In the past decade, new evidence has emerged of a physiological role for C-peptide. C-peptide replacement improves renal and nerve function and augments regional blood flow in type I diabetic patients. READ MORE

  7. 15. Molecular mechanisms underlying the glucose-dependent transcription of the insulin and glucokinase genes in the pancreatic beta-cell

    Author : Tilo Moede; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Insulin is of vital importance in the maintenance of the glucose homeostasis in mammals. This necessitates a tight regulation of both insulin release and biosynthesis. READ MORE