Search for dissertations about: "Akt PKB"

Showing result 16 - 20 of 22 swedish dissertations containing the words Akt PKB.

  2. 16. A multifaceted study of the receptor tyrosine kinase Axl with focus on Renal Cell Carcinoma

    Author : Anna Gustafsson; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The present investigation is a multifaceted study of the receptor tyrosine kinase Axl, whose overexpression and activation is implicated in several human malignancies, with focus on renal cell carcinoma (RCC). At first, our main interest concerned the intracellular Axl interactor named Tensin2 (Tns2) and its family member Tensin3 (Tns3). READ MORE

  4. 17. Microbe-induced apoptosis in phagocytic cells and its role in innate immunity

    Author : Robert Blomgran; Olle Stendahl; Limin Zheng; Boris Zhivotovsky; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; apoptosis; cell death; inflammation; innate immunity; microbiology; neutrophil; macrophage; phagocyte; Medical microbiology; Medicinsk mikrobiologi;

    Abstract : Apoptosis, or programmed cell death, is a controlled process by which aged or damages cells are eliminated in multicellular organisms. Neutrophils, short-lived phagocytes of the innate immune system, are highly equipped effectors that can sense, locate, ingest and kill bacterial pathogens. READ MORE

  5. 18. Signal transduction in human phagocytic cells during phagocytosis, oxidative activation and apoptosis

    Author : Maria Forsberg; Emmanuelle Caron; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Neutrophils and macrophages are professional phagocytic cells that play a crucial role in host defense against invading microorganisms. They bind to, internalize, and subsequently kill microbes with an arsenal of reactive oxygen metabolites and microbicidal agents. READ MORE

  6. 19. Neuropeptides and neurotransmitters in keratocytes : importance in corneal wound healing processes

    Author : Marta Sloniecka; Patrik Danielson; May Griffith; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; substance P; acetylcholine; migration; proliferation; apoptosis; corneal stroma;

    Abstract : Background: The cornea is the outermost transparent layer of the eye and it is responsible for the majorityof the eye’s total focusing power. Keratocytes are the resident cells of the corneal stroma and their function isto produce extracellular matrix components and to take part in corneal healing after injury, which may occurdue to trauma, infection or surgery. READ MORE

  7. 20. Insulin signalling in human adipocytes : mechanisms of insulin resistance in type 2 diabetes

    Author : Anna Danielsson; Peter Strålfors; Fredrik Nyström; Lena Stensson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipocytes; type 2 diabetes; insulin; insulin resistance; insulin signalling; phosphorylation; insulin receptor substrate 1; feedback control; Medical cell biology; Medicinsk cellbiologi;

    Abstract : Prevalensen av fetma ökar drastiskt i stora delar av världen och utgör en stor riskfaktor för att utveckla insulinresistens och typ 2 diabetes. Fettväven kan bli mycket stor om för mycket energi tas upp av kroppen. READ MORE