Search for dissertations about: "Akt"

Showing result 21 - 25 of 223 swedish dissertations containing the word Akt.

  2. 21. PKB/Akt kinase localization and role in stemness maintenance in cancer

    Author : Mayur Vilas Jain; Karin Roberg; Piotr Religa; Mehrdad Rafat; Mahvash Tavassoli; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Cancer incidence rates have increased over the last decade. Currently available therapies are only moderately effective in targeting cancer cells. Established cancer treatment protocols fail to eliminate populations of cancer stem cells (CSCs), which develop resistance against the chemotherapeutic drugs and lead to cancer recurrence. READ MORE

  4. 22. Analyses of Akt and PDGF receptor expression and activation in human tumors

    Author : Janna Paulsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : These studies aimed at developing methodology for detection of proteins involved in cancer and the evaluation of their prognostic significance in human tumors. Signal transduction profiling of tumors are becoming increasingly interesting based on the accumulating evidence of its prognostic and drug response-predicative value. READ MORE

  5. 23. The importance of Akt downstream the beta-adrenergic receptors in brown adipose tissue

    Author : Alice Åslund; Tore Bengtsson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; molekylär biovetenskap; Molecular Bioscience;

    Abstract : .... READ MORE

  6. 24. Molecular mechanisms of insulin resistance with special emphasis on IRS-1 and PKB/Akt

    Author : Eugénia Carvalho; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Insulin; insulin resistance; diabetes; protein kinase B; insulin receptor substrate-1; insulin signalin; Glute-4; PI 3-kinase; glucose transport; adipose tissue;

    Abstract : .... READ MORE

  7. 25. Alterations in the PI3K/AKT Signaling Pathway and Response to Adjuvant Treatment in Breast Cancer

    Author : Gizeh Pérez-Tenorio; Olle Stål; Anne Lykkesfeldt; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Onkologi;

    Abstract : (PI3K)/AKT signaling pathway could be a cause of therapeutic resistance in breast cancer. The PI3K/AKT pathway controls cell proliferation, cell growth and survival, and its members include oncogenes and tumor suppressor genes. Alterations in this pathway are frequent in cancer. READ MORE