Search for dissertations about: "Alan Sabirsh"
Found 2 swedish dissertations containing the words Alan Sabirsh.
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1. Molecular Pharmacology and Structure Function Modelling of the Leukotriene B4 Receptor BLT1
Abstract : Leukotrienes are membrane derived bioactive lipids that play an important role in immune responses by initiating and maintaining the inflammatory responses. Leukotriene B4 (LTB4) released at the site of an inflammatory response attracts, activates and prolongs the life of leukocytes and lymphocytes. READ MORE
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2. Lysosomal network proteins as biomarkers and therapeutic targets in neurodegenerative disease
Abstract : The pre-symptomatic stage of neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD) occurs several decades before the clinical onset. Changes in the lysosomal network, i.e. the autophagosomal, endosomal and lysosomal vesicular system, are among the first alterations observed. READ MORE