Search for dissertations about: "Aldehyd"

Found 5 swedish dissertations containing the word Aldehyd.

  2. 1. Synthesis of Aldehyde-Functionalized Building Blocks and Their Use for the Cyclization of Peptides : Applications to Angiotensin II

    Author : Petra Johannesson; Rob M. J. Liskamp; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Synthesis; Aldehyde; Cyclization; Peptide; Angiotensin II; Ang II; Bioactive Conformation; Solid Phase Peptide Synthesis; Dimethyl Acetal; Farmaceutisk kemi; Syntes; Aldehyd; Cyklisering; Peptid; Bioaktiv konformation; Fast-fas peptidsyntes; Dimetylacetal; Pharmaceutical chemistry; Farmaceutisk kemi; Organic Pharmaceutical Chemistry; organisk farmaceutisk kemi;

    Abstract : This study addresses the issue of how to convert peptides into drug-like non- peptides with retained biological activities at peptide receptors. Angiotensin II (Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, Ang II) was used as a model peptide. READ MORE

  4. 2. Highly enantioselective synthesis of lactam and sugar derivatives by chiral aminocatalysis and merging with transition metal catalysis

    Author : Zhang Kaiheng; Armando Cordova; Malkov Andrei; Mittuniversitetet; []
    Keywords : ;

    Abstract : This thesis presented novel methodologies for enantioselectivesynthesis of highly functionalized lactam and sugar derivatives.Asymmetric organocatalysis, cooperative dual catalysis and one-pot multicomponent reaction strategies were applied for the construction of continuous and quaternary stereogenic center. READ MORE

  5. 3. Assessing carotid plaque structure

    Author : Isabel Goncalves; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; Kardiovaskulära systemet; Modified LDL; Antibodies; Lipids; AP-1; Cellularity; Extracellular Matrix; Calcification; Elastin; Stroke; Gray-Scale Median; Echogenicity; Ultrasound; Atherosclerosis; Carotid Plaque;

    Abstract : Atherosclerosis is the leading cause of death and disability in the western world. Its clinical complications include acute myocardial infarction, sudden death and stroke. Thirty to 40 % of all ischemic strokes are caused by a carotid stenosis. READ MORE

  6. 4. A Catalytic and Mechanistic Investigation of Palladium-Phosphine Catalysed Aqueous Hydroxycarbonylation. Steric and Electronic Properties of the Ligands

    Author : Adriana Ionescu; Kemiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Oorganisk kemi; Inorganic chemistry; Naturvetenskap; Natural science; Isomerisation of hydroxyalkenes; Mechanism; Regioselectivity; Steric and electronic properties; Hydroxycarbonylation of styrene; Water-soluble phosphines; Palladium; Aqueous catalysis;

    Abstract : The steric and electronic properties of eight water-soluble phosphines (1-8) were investigated by different methods. Phosphines 1-6 were tested as ligands in palladium catalysed hydroxycarbonylation of styrene. READ MORE

  7. 5. Fatty Acyl Reductases and Fatty Acyl Desaturases. Deciphering the biosynthesis of species-specific moth female sex pheromones from common fatty acids

    Author : Åsa Hagström; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Moth; pheromone; insect; evolution; fatty acyl desaturase; fatty acyl reductase; endoplasmic reticulum; fatty acid biosynthesis; GFP; heterologous expression; phylogeny; cell factory; lepidoptera;

    Abstract : Moths (Lepidoptera) are dependent on female produced pheromones, chemical signals, for attracting a mate. Pheromones are most commonly made up by saturated and/or unsaturated fatty acid derived alcohols, acetates, and/or aldehydes that are produced by a set of enzymes in the female pheromone gland. READ MORE