Search for dissertations about: "Aleksandra"

Showing result 1 - 5 of 45 swedish dissertations containing the word Aleksandra.

  2. 1. Epidemiology of osteoarthritis in Sweden. Register and cohort studies on prevalence and mortality

    Author : Aleksandra Turkiewicz; Lund Ortopedi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epidemiology; Osteoarthritis; Knee; Hip; Radiography; Mortality; Registers; Missing data;

    Abstract : Osteoarthritis (OA) is the most common form of arthritis and often causes pain and functional impairment. Despite its high burden on society, knowledge about the occurrence of OA and its associated mortality is sparse. READ MORE

  4. 2. Exploring molecular interactions between polypeptide conjugates and protein targets : Manipulating affinity by chemical modifications

    Author : Aleksandra Balliu; Lars Baltzer; Oliver Seitz; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; polypeptide conjugates; protein targets; molecular recognition; affinity enhancement; conjugation;

    Abstract : In this thesis molecular interactions between polypeptide conjugates and protein targets were investigated. Polypeptides were derivatized with small organic molecules, peptides and oligonucleotides. New strategies were developed with the aim to increase affinities for proteins of biological interest. READ MORE

  5. 3. Hyperconjugation in Group 14 Organic Compounds : Design and Property Investigations

    Author : Aleksandra Denisova; Henrik Ottosson; Thomas Müller; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; 1; 4-disilacyclohexa-2; 5-diene; aromaticity; computational chemistry; conjugation; cross-hyperconjugation; hyperconjugation; group 14 elements; organosilicon chemistry; silole;

    Abstract : Nowadays π-conjugated molecules are widely used as materials for devices in organic and molecular electronics. This is due to the ability of such molecules to conduct electricity. However, π-conjugation leads to molecular rigidness and associated lower solubility, which limits possible applications. READ MORE

  6. 4. Clinical consequences of pancreatic exocrine insufficiency

    Author : Aleksandra Hedström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Chronic pancreatitis (CP) is characterized by a chronic inflammation with fibrosis and irreversible morphological changes that can result in permanent structural changes with a loss of exocrine and endocrine pancreas function. Exocrine dysfunction leads to reduced production of pancreatic digestive enzymes which is the reason of maldigestion and malabsorption of ingested nutrients like fats, microelements, vitamins and proteins which can lead to osteopathy. READ MORE

  7. 5. Depression and cognition in the elderly : neuroimaging perspective

    Author : Aleksandra Lebedeva; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis examines the relationship between depression and brain structure in the elderly with (Study I, III) and without (Study II, IV) cognitive impairment (Alzheimer’s disease and mild cognitive impairment). Individuals from four independent cohorts were included. READ MORE