Search for dissertations about: "Allele sharing"

Showing result 11 - 15 of 15 swedish dissertations containing the words Allele sharing.

  2. 11. Novel statistical methods for genome-wide association summary statistics

    Author : Zheng Ning; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : A general objective of genetic studies is to understand the genetic basis of complex traits such as height, body mass index (BMI), disease endpoints, etc. Such researches have been facilitated due to the completion of the human genome project and developments of high-throughput technologies. READ MORE

  4. 12. Susceptibility gene mapping in multiple sclerosis

    Author : Bing He; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is a chronic inflammatory disease characterized by relapsing or progressive demyelination of the central nervous system (CNS). Increasing evidence supports that genetic factors confer susceptibility to MS resulting in an unknown mode of inheritance as a complex trait. READ MORE

  5. 13. Recurrent spontaneous abortion : a clinical, immunological and genetic study

    Author : Barbara Jablonowska; Ole Christiansen B.; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Recurrent spontaneous abortion (RSA) is defined as the loss of three or more consecutive pregnancies before 20 completed gestational weeks. The condition affects 0.5-1% of all women. In the majority of women with RSA, the cause remains unexplained after genetic, endocrine, immunological and anatomical investigations of the couple. READ MORE

  6. 14. Genetic basis of congenital nephrotic syndrome and generation of an animal model

    Author : Heli Putaala; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Congenital nephrotic syndrome, NPHS1, is a disease highly enriched in Finland with incidence of 1:8200 births. The disease is characterized by massive proteinuria, go % of which is albumin, starting in utero, large placenta, which weighs over 25 % of the child's birth weight, and manifestation of proteinuria soon after birth. READ MORE

  7. 15. Genetic and environmental factors in relation to childhood type 1 diabetes mellitus aetiology and clinical presentation in Sweden and Lithuania

    Author : Vaiva Sadauskaite-Kühne; Johnny Ludvigsson; Knut Borch-Johnsen; Linköpings universitet; []
    Keywords : Type 1 diabetes mellitus; children; environmental factors; aetiology; MEDICINE; MEDICIN;

    Abstract : Background. Incidence of Type I diabetes mellitus (DM) is increasing worldwide. It is affecting mostly young people, with the dramatically rising incidence among youngest children (those under age of 5 years). READ MORE