Search for dissertations about: "Allogenic cell therapy"

Showing result 1 - 5 of 11 swedish dissertations containing the words Allogenic cell therapy.

2. 1. Magnetic bead-based isolation of biological therapeutic modalities

   Author : Nils A. Brechmann; Véronique Chotteau; Nigel Titchener-Hooker; KTH; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Magnetic bead separation; Magnetic beads; Protein A; Protein G; Negative cell isolation; Monoclonal antibody; induced pluripotent stem cells; human mesenchymal stem cells; Allogenic cell therapy; Biomanufacturing; cell clarification; Biotechnology; Bioteknologi;

   Abstract : Biopharmaceutical modalities, such as monoclonal antibodies or the less established cell therapies, are nowadays very important for the treatment of severe or incurable diseases. The manufacturing of such modalities is complex and costly, including the downstream processing, which is highly essential to ensure the safety and quality of the product. READ MORE

4. 2. Natural killer cell development and function in the context of allogenic stem cell transplantation and cell therapy

   Author : Alvaro Haroun-Izquierdo; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Natural killer (NK) cells play a crucial role in the control of viral infections and transformed, cancerous cells. These innate cells have high cytotoxic capacities and use a multitude of receptors to interact with neighbouring cells. READ MORE

5. 3. Gene therapy in a new model of delayed wound healing

   Author : Patrik Velander; Kirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IGF-1; Gene therapy; Diabetes; Animal model; EGF;

   Abstract : Diabetes wounds result in significant morbidity, prolonged hospitalization and huge health care expenses. As of yet, no optimal animal models of diabetic wound healing exist to study potential beneficial therapies. Porcine wound healing is very similar to human wound healing. READ MORE

6. 4. Molecular monitoring of acute graft-versus-host disease after allogenic stem cell transplantation

   Author : Marie Jaksch; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Stem Cell Transplantation; Acute Graft-versus-host disease; FasL; Granzym B; Chemokine receptors; chimerism;

   Abstract : Acute graft-versus-host disease (GVHD) remains a major barrier to the wider application of allogeneic stem cell transplantation (SCT) for a variety of diseases. GVHD occurs when the transplanted donor Tlymphocytes react to host antigens on antigen-presenting cells and attack host tissues. READ MORE

7. 5. Mesenchymal stromal cell crosstalk with the immune system

   Author : Caroline Gavin; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Cell therapy is a promising treatment for several diseases. One of the most commonly used cell types are mesenchymal stromal cells (MSCs). MSCs are found in most connective tissues but for clinical use they are commonly harvested from bone marrow, adipose tissue and umbilical cord. READ MORE