Search for dissertations about: "Alpha irradiation"

Showing result 1 - 5 of 21 swedish dissertations containing the words Alpha irradiation.

  2. 1. Cellular responses to combined irradiation with alpha particles and X-rays

    Author : Alice Sollazzo; Andrzej Wojcik; Alexandros Georgakilas; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Radiation; DNA damage; mutations; alpha particles; X-rays; mixed beam; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Mixed radiation fields, where different ionizing particles act together, are very important in radiobiology and in radiation protection. Mixed beams are not only the most common form of radiation exposure, but the prediction of their biological effect is also full of uncertainties. READ MORE

  4. 2. Skull base meningioma : Surgical and adjuvant treatment with clinical and PET evaluation

    Author : Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Meningioma; cerebellopontine angle; translabyrinthine and transcochlear approaches; facial nerve; steretactic irradiation; proton beam therapy; interferon- alpha; PET; 11C-L-methionine; 76BR-BrdU; Neurovetenskap; Neurology; Neurologi; Medicine; medicin;

    Abstract : The treatment strategy for skull base meningiomas remains a controversial issue. Because of the proximity of these tumours to critical neurovascular structures, the risk for vascular damage and new cranial neuropathies postoperatively is significant. READ MORE

  5. 3. Alpha-radioimmunotherapy with At-211: Evaluations and imaging on normal tissues and tumors

    Author : Tom Bäck; Göteborgs universitet; []
    Keywords : radioimmunotherapy; astatine; RBE; renal function; GFR; imaging; targeted radiotherapy; alpha-RIT;

    Abstract : Alpha-radioimmunotherapy (alpha-RIT) is an internal conformal radiotherapy at the cellular level using alpha-particle emitting radionuclides. Alpha-particles have a very short range in tissues (... READ MORE

  6. 4. Astatine-211 radioimmunotherapy of ovarian cancer. Therapeutic efficacy, myelotoxicity, andradiation dosimetry in an animal model

    Author : Jörgen Elgqvist; Göteborgs universitet; []
    Keywords : astatine; alpha-particles; monoclonal antibodies; radioimmunotherapy; ; ovarian cancer; myelotoxicity; therapeutic efficacy; radiation dosimetry; fractionation;

    Abstract : Alpha-particle emitting radionuclides have recently obtained an increased attention whenconsidering new strategies for treating disseminated cancer. Astatine (211At), that emits alphaparticleswith a mean path length of 62 μm, a mean linear energy transfer (LET) of 111keV/Mum, and a half-life of 7. READ MORE

  7. 5. Pharmacokinetics and dosimetry in intraperitoneal radioimmunotherapy with 211At

    Author : Elin Cederkrantz; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; astatine-211; radioimmunotherapy; alpha-emitter; ovarian cancer; MX35; pharmacokinetics; dosimetry; effective dose;

    Abstract : The prognosis for patients diagnosed with disseminated cancer is often poor. Radioimmunotherapy (RIT) is a new approach to treat disseminated disease. The aim is to target tumor cells with monoclonal antibodies (mAbs) labeled with radionuclides which release cytotoxic particle radiation upon decay. The radionuclide 211At, with half-life 7. READ MORE