Search for dissertations about: "Alternative Splicing"
Showing result 11 - 15 of 124 swedish dissertations containing the words Alternative Splicing.
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11. Functional Characterization of the Cellular Protein p32 : A Protein Regulating Adenovirus Transcription and Splicing Through Targeting of Phosphorylation
Abstract : Cellular processes involved in the conversion of the genetic information from DNA into a protein are often regulated by reversible phosphorylation reactions. By modulating the phosphorylated status of key proteins their activity can either be enhanced or repressed. READ MORE
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12. Ligation-mediated Molecular Analysis of Influenza Subtypes, Splicing and Protein Glycosylation
Abstract : Binder-based assays are employed throughout the life sciences. Powerful signal amplification techniques have enabled detection of very rare molecule species diluted in simple buffers. Unspecific binding of primary binders leads to increased background in more complex samples. READ MORE
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13. Adenovirus vector systems permitting regulated protein expression and their use for in vivo splicing studies
Abstract : We have constructed two adenovirus-based gene expression vector systems permitting regulated protein expression. They are based on the tetracycline-regulated Tet-ON- and the progesterone antagonist RU 486-regulated gene expression systems, which were rescued into E1-deficient adenovirus vectors. READ MORE
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14. Regulation of RNA Processing in Human Papillomavirus Type 16
Abstract : Human papillomavirus type 16 (HPV-16) is the major cause of cervical cancer. HPV-16 gene expression is tightly linked to the differentiation programme of the infected epithelium. Expression of the late genes, L1 and L2, encoding the capsid proteins, is delayed until the more terminally differentiated cells. READ MORE
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15. Viral Control of SR Protein Activity
Abstract : Viruses modulate biosynthetic machineries of the host cell for a rapid and efficient virus replication. One important way of modulating protein activity in eukaryotic cells is by reversible phosphorylation. In this thesis we have studied adenovirus and vaccinia virus, two DNA viruses with different replication stategies. READ MORE