Search for dissertations about: "Alzheimer s disease"

Showing result 11 - 15 of 79 swedish dissertations containing the words Alzheimer s disease.

  2. 11. Oxidative mechanisms in London Familial Alzheimer´s disease and LPS-induced inflammation

    Author : Katarina Reis; Tiit Land; Maria de Sousa; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurochemistry; Neurokemi; Neurochemistry and Molecular Neurobiology; neurokemi med molekylär neurobiologi;

    Abstract : Alzheimer´s disease (AD) is the most common of the progressive neurodegenerative disorders and is characterized by the formation of Aβ deposits, neurofibrillary tangles and loss of neurons. Additional features of the disease are inflammation, increased oxidative stress and modified iron metabolism. READ MORE

  4. 12. Mental stimulation and multimodal trials to prevent cognitive impairment and Alzheimer ́s disease

    Author : Anders Rydström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Theoretical models of dynamic biomarkers underlying the development of Alzheimer´s Disease (AD) acknowledge that there is inter-individual variability in the cognitive performance associated with any level of AD pathology. Mentally stimulating activities such as schooling, occupation, and leisure activities, may contribute to this variability, but it is yet unclear how this can be best assessed, and how such effects can vary across AD severity and among individuals at-risk for cognitive impairment. READ MORE

  5. 13. Genetic variation in genes involved in Abeta-degradation in Alzheimer disease

    Author : Mia Blomqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Alzheimer disease; SNPs; genotyping; association study; haplotype; linkage disequilibrium; association mapping;

    Abstract : Alzheimer disease (AD) is a neurodegenerative disorder that causes dementia among mainly elderly people and is increasing in prevalence in industrialized societies from 1 to 3 % in 60-65 year-olds to as much as 50 % by age 95. This disease is complex. Multiple genes are involved, and they potentially affect each other. READ MORE

  6. 14. Alzheimer´s disease-related amyloid precursor protein and presenlin genes : normal function and pathophysiology

    Author : Fiona Flood; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Alzheimer's disease (AD) is characterised neuropathologically by the presence of plaques and tangles in the brain. AD can be sub-grouped into early onset (EOAD, age of onset ... READ MORE

  7. 15. Periodontal disease and cognitive disorders

    Author : Jacob Holmer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Periodontitis and tooth loss have been suggested to be putative aetiological risk factors for dementia and cognitive dysfunction. The identification of new dementia risk factors could lead to new preventive strategies for dementia. READ MORE