Search for dissertations about: "Alzheimers diseases"

Showing result 1 - 5 of 201 swedish dissertations containing the words Alzheimers diseases.

  2. 1. Mass Spectrometry of Non-protein Amino Acids : BMAA and Neurodegenerative Diseases

    Author : Liying Jiang; Leopold Ilag; Jonas Bergquist; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Neurodegenerative diseases; BMAA; Isomers; LC-MS MS; Cyanobacteria; Diatoms; Seafood contamination; Analytical Chemistry; analytisk kemi;

    Abstract : Neurodegenerative diseases have been shown to correlate positively with an ageing population. The most common neurodegenerative diseases are amyotrophic lateral sclerosis (ALS), Parkinson’s disease and Alzheimer’s disease. READ MORE

  4. 2. Implications of Heparan Sulfate and Heparanase in Inflammatory Diseases

    Author : Andreas Digre; Jin-Ping Li; Lena Kjellén; Liliana Schaefer; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparanase; Heparan sulfate; Inflammation; Inflammatory diseases; Autoimmune diseases; Amyloidosis; Reumathoid arthritis; SAA; APP; A beta; Neuroinflammation; Medical Science; Medicinsk vetenskap; Medical Biochemistry; Medicinsk biokemi; Immunologi; Immunology; Neurology; Neurologi;

    Abstract : Heparan sulfate (HS), an unbranched sulfated carbohydrate chain, and the HS-degrading enzyme heparanase play important roles in physiological and pathological processes during all stages of life, from early embryogenesis to ageing. Accumulated information shows that HS and heparanase are involved in inflammatory processes and associated diseases, e. READ MORE

  5. 3. Susceptibility genes in conformational diseases

    Author : Malin von Otter; Göteborgs universitet; []
    Keywords : Conformational disease; Alzheimer’s disease; Parkinson’s disease; Cataract Protein aggregation; Cellular transport; Oxidative stress; Susceptibility; genes; SNP; Haplotype;

    Abstract : Conformational diseases are characterized by protein misfolding and aggregation in the affected tissue. The aim of this thesis was to find genetic support for mechanisms in common for three prevalent ... READ MORE

  6. 4. Ex‘PLA’ining the progression of pathological proteins in Alzheimer’s and Parkinson’s diseases : see(d)ing is believing

    Author : Anish Behere; Joakim Bergström; Sara Ekmark-Lewén; Martin Ingelsson; Stina Syvänen; Hilal Lashuel; Uppsala universitet; []
    Keywords : Alpha synuclein; Tau; Proteoforms; Phosphorylation; Oligomers; Proximity Ligation Assay; sensitive detection of pathology; Alzheimer s disease; Parkinson s disease; pS129; pS202 pT205; pT231; PFFs;

    Abstract : Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the two most common forms of neurodegenerative disorders affecting approximately 50 million people worldwide. The underlying neuropathological processes leading to AD and PD share many similarities, i.e. aberrant protein aggregation of tau and alpha-synuclein (αSyn) in the brain. READ MORE

  7. 5. Fragile identities, patched-up worlds : Dementia and meaning-making in social interaction

    Author : Linda Örulv; Lars-Christer Hydén; Nina Nikku; Staffan Josephsson; Linköpings universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Alzheimer’s disease; communication; confabulation; context; continuity; dignity; disorientation; ethnographic methods; ethnography; identity; life history; life story; meaning; microethics; narrative; progressive dementia diseases; sense-making; social interaction; storytelling; vascular dementia; Alzheimers sjukdom; berättande; desorientering; etnografiska metoder; identitet; kommunikation; konfabulering; kontext; kontinuitet; livsberättelse; mening; mikroetik; narrativ; progressiva demenssjukdomar; samspel; social interaktion; vaskulärdemens; värdighet; Human communication; Kommunikation mellan människor;

    Abstract : Denna avhandling fokuserar på det meningsskapande och begripliggörande som fortgår vid tilltagande demenssjukdom, i det sociala samspelet, och de utmaningar för demens-omsorgen som detta innebär. Studien är aktörsorienterad och adresserar frågan om hur personer med åldersrelaterade progressiva demenssjukdomar i den vardagliga kommuni-kationen söker förstå sina situationer, omgivningen och sina liv – alltsammans inom ra-men för det dagliga samspelet på ett demensboende. READ MORE