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Showing result 1 - 5 of 59 swedish dissertations matching the above criteria.

2. 1. Stress steroids as accelerators of Alzheimer's disease. : Effects of chronically elevated levels of allopregnanolone in transgenic AD models

   Author : Sara Bengtsson; Mingde Wang; Torbjörn Bäckström; Maja Johansson; Caroline Graff; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Allopregnanolone; Alzheimer s disease; beta-amyloid; synaptophysin; chronic stress; Morris water maze; obstetrik och gynekologi; Obstetrics and Gynaecology; medicinsk farmakologi; Medical Pharmacology; Neurology; neurologi; Geriatrics; geriatrik; medical behavioral science; medicinsk beteendevetenskap;

   Abstract : Background Alzheimer’s disease (AD) and dementia are devastating con­ditions not only for the affected patients but also for their families.  The economical costs for the society are tremendous. READ MORE

4. 2. Cognitive erosion and its implications in Alzheimer’s disease

   Author : Selina Mårdh; Thomas Karlsson; Anders Wallin; Linköpings universitet; []
   Keywords : Alzheimer’s disease; longitudinal study; mixed methods design; semantic memory; awareness; metacognition; central coherence; emotions; Alzheimers sjukdom; longitudinell studie; mixed methods design; semantiskt minne; medvetande; metakognition; central koherens; emotioner; Do Psychology;

   Abstract : The aim of the present thesis was twofold, first to map the semantic memory decline in Alzheimer patients over time, second to take the patient’s perspective and create a multifaceted picture of the individual with Alzheimer’s disease through the study of memory, awareness, central coherence and emotions. Further issues concerned how Alzheimer individuals handled their cognitive erosion in everyday life and if they were well calibrated with their spouse in disease related matters. READ MORE

5. 3. Remembering in Alzheimer's disease : utilization of cognitive support

   Author : Agneta Herlitz; Lars-Göran Nilsson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; Dementia; Memory; Episodic memory; Semantic memory; Severity of dementia; Alzheimers sjukdom; demens; minne;

   Abstract : The aim of the present doctoral thesis was to investigate the ability of patients with Alzheimer's disease (AD) to utilize cognitive support in order to improve episodic remembering. A review of previous research indicated that most studies have failed to find beneficial effects of encoding support on memory in AD patients. READ MORE

6. 4. Fragile identities, patched-up worlds : Dementia and meaning-making in social interaction

   Author : Linda Örulv; Lars-Christer Hydén; Nina Nikku; Staffan Josephsson; Linköpings universitet; []
   Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Alzheimer’s disease; communication; confabulation; context; continuity; dignity; disorientation; ethnographic methods; ethnography; identity; life history; life story; meaning; microethics; narrative; progressive dementia diseases; sense-making; social interaction; storytelling; vascular dementia; Alzheimers sjukdom; berättande; desorientering; etnografiska metoder; identitet; kommunikation; konfabulering; kontext; kontinuitet; livsberättelse; mening; mikroetik; narrativ; progressiva demenssjukdomar; samspel; social interaktion; vaskulärdemens; värdighet; Human communication; Kommunikation mellan människor;

   Abstract : Denna avhandling fokuserar på det meningsskapande och begripliggörande som fortgår vid tilltagande demenssjukdom, i det sociala samspelet, och de utmaningar för demens-omsorgen som detta innebär. Studien är aktörsorienterad och adresserar frågan om hur personer med åldersrelaterade progressiva demenssjukdomar i den vardagliga kommuni-kationen söker förstå sina situationer, omgivningen och sina liv – alltsammans inom ra-men för det dagliga samspelet på ett demensboende. READ MORE

7. 5. Validation of brief cognitive tests in mild cognitive impairment, Alzheimer's disease and dementia with Lewy bodies

   Author : Sebastian Palmqvist; Klinisk minnesforskning; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cognitive tests; neuropsychology; Alzheimer’s disease; dementia with Lewy bodies; mild cognitive impairment; treatment evaluation; acetylcholinesterase inhibitors; differential diagnosis; longitudinal studies; dementia; cerebrospinal fluid; forecasting;

   Abstract : Background It is estimated that 34 million people suffer from dementia, costing society US$422 billion each year. Alzheimer’s disease (AD) is the most common dementia and the global prevalence is predicted to increase to over 100 million people by the year 2050, with the greatest increase in developing countries. READ MORE