Search for dissertations about: "Amino Acid Radicals"

Showing result 6 - 10 of 18 swedish dissertations containing the words Amino Acid Radicals.

  2. 6. Regulation of Proton Coupled Electron Transfer from Amino Acids in Artificial Model Systems: A Mechanistic Study

    Author : Martin Sjödin; Leif Hammarström; Jan Davidsson; G. Daniel Nocera; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; Proton Coupled Electron Transfer; Tyrosine; Tryptophan; Electron Transfer; Hydrogen bond; Photosystem II; Proton transfer; Radical protein; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi;

    Abstract : Amino acid radicals are key redox intermediates in several natural enzymes including Cytochrome c peroxidase, DNA photolyase, ribonucletide reductase, cytochrome c oxidase and photosystem II. Electron transfer from amino acids is often coupled to deprotonation and this thesis concerns the coupling of electron transfer from tyrosine and tryptophan to trisbipyridineruthenium(III) with deprotonation in model complexes. READ MORE

  4. 7. Age pigments and the biochemical basis of their formation

    Author : Dazhong Yin; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The autofluorescent, yellow-brown pigments that accumulate over time inbiological organisms are called age pigments. Lipofuscin, known as a hallmark of aging, refers to intracellular age pigments that accumulate mainly in the lysosomes of postrnitotic cells. READ MORE

  5. 8. Protection of Biomolecules by Antioxidants - Mechanisms and Applications

    Author : Carl Grey; Bioteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; dG; antioxidants; mass spectrometry; Analytical chemistry; Analytisk kemi; Food and drink technology; Livsmedelsteknik; Bioteknik; Biotechnology; DNA; Oxidation; Protein; Fenton reaction;

    Abstract : Reactive oxygen species (ROS) consisting of various oxygen-based free radicals as well as other reactive non-radical species produced in O2-related metabolism or through other processes are involved in the oxidation of such vital biomolecules as DNA, proteins and lipids. The types of oxidation represented here are known to cause many different diseases and disorders in human beings, such as cancer, Alzheimer's disease and ageing. READ MORE

  6. 9. The influence of nucleotides on ribonucleotide reductase assambly in class I ribonucleotide reductase from Escherichia coli

    Author : Pernilla Larsson Birgander; Britt-Marie Sjöberg; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi;

    Abstract : The components of DNA, the deoxyribonucleotides, are produced from the components of RNA, the ribonucleotides. One single substitution is needed to convert a ribonucleotide into a deoxyribonucleotide i.e. a replacement of a hydroxyl group with a hydrogen atom. READ MORE

  7. 10. A radical view of haemoglobin - protein engineering and characterisation

    Author : Marie Grey; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; His-Gln tagging; protein purification; blood substitutes; radical scavenging; superoxide dismutase; E. coli; diglobin; Haemoglobin; protein engineering; aqueous two-phase systems; hydrophobic interaction chromatography;

    Abstract : In recent years shortages of donated blood have become a growing problem for health care systems world-wide. Blood substitutes based on human haemoglobin (Hb) could potentially ameliorate this situation. However, clinical trials have indicated problems due to e.g. READ MORE