Search for dissertations about: "Aminoglycoside"

Showing result 6 - 10 of 27 swedish dissertations containing the word Aminoglycoside.

  2. 6. Antibiotic Resistance in Wastewater : Methicillin-resistant Staphylococcus aureus (MRSA)and antibiotic resistance genes

    Author : Stefan Börjesson; Per-Eric Lindgren; Johanna Ericson Sollid; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MRSA; SCCmec; spa typing; Staphylococcus aureus; methicillin; B-lactam; aminoglycoside; tetracycline; antibiotic; wastewater; wastewater treatment plant; Microbiology; Mikrobiologi;

    Abstract : A large part of the antibiotics consumed ends up in wastewater, and in the wastewater the antibiotics may exert selective pressure for or maintain resistance among microorganisms. Antibiotic resistant bacteria and genes encoding antibiotic resistance are commonly detected in wastewater, often at higher rates and concentrations compared to surface water. READ MORE

  4. 7. Molecular Interplay of Antibiotics on the Bacterial Ribosome

    Author : Narayan Prasad Parajuli; Suparna Sanyal; Michael Y. Pavlov; Chandra Sekhar Mandava; Axel Innis; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Ribosome; Translation; Antibiotics; Aminoglycoside; Thermorubin; Protein synthesis; Molekylär biovetenskap; Molecular Life Sciences;

    Abstract : Inhibition of protein synthesis is one of the most common modes of action for medically useful antibiotics. This thesis presents the mechanistic studies of two chemically distinct classes of antibiotics that target bacterial ribosomes –aminoglycosides and thermorubin. READ MORE

  5. 8. Blood Culture Negative Endocarditis

    Author : Maria Werner; Göteborgs universitet; []
    Keywords : Infective endocarditis IE ; Blood culture negative endocarditis CNE ; Blood culture; Diagnosis; Mortality; Bartonella; Coxiella burnetii; Chlamydophila pneumoniae; Prevalence; Aminoglycoside;

    Abstract : The lethal disease infective endocarditis (IE) is caused by microorganisms that attack heart valves. Early diagnosis and identification of the causative agents are important for the choice of treatment. Optimal treatment may be difficult to achieve if blood culture negative endocarditis (CNE) is present. READ MORE

  6. 9. Structural and Biochemical Studies of Antibiotic Resistance and Ribosomal Frameshifting

    Author : Yang Chen; Maria Selmer; Dominique Fourmy; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein synthesis; elongation; elongation factor G; fusidic acid; antibiotic resistance; aminoglycoside adenyltransferase; ribosomal frameshifting; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi;

    Abstract : Protein synthesis, translation, performed by the ribosome, is a fundamental process of life and one of the main targets of antibacterial drugs. This thesis provides structural and biochemical understanding of three aspects of bacterial translation.Elongation factor G (EF-G) is the target for the antibiotic fusidic acid (FA). READ MORE

  7. 10. Chromosomal antibiotic resistance mechanisms in Pseudomonas aeruginosa and Neisseria gonorrhoeae

    Author : Sohidul Islam; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The progressive increase in fluoroquinolone resistant N. gonorrhoeae and emergence of multiple antibiotic resistant P. aeruginosa are growing concerns among physicians and health policy makers. In N. READ MORE