Search for dissertations about: "Aminolevulinic acid"

Showing result 1 - 5 of 17 swedish dissertations containing the words Aminolevulinic acid.

  1. 1. 5-Aminolevulinic acid and derivatives thereof : properties, lipid permeability and enzymatic reactions

    Author : Edvin Erdtman; Leif Eriksson; Tore Brinck; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 5-Aminolevulinic acid; tautomerization; PDT; DFT; MM; QM MM; Porphobilinogen synthase; Uroporphyrinogen III decarboxylase; membrane penetration; enzyme mechanism; Biophysical chemistry; Biofysikalisk kemi; Quantum chemistry; Kvantkemi; Theoretical chemistry; Teoretisk kemi; Fysikalisk kemi; Physical Chemistry; Biochemistry; Biokemi;

    Abstract : 5-aminolevulinic acid (5-ALA) and derivatives thereof are widely usedprodrugs in treatment of pre-malignant skin diseases of the cancer treatmentmethod photodynamic therapy (PDT). The target molecule in 5-ALAPDTis protoporphyrin IX (PpIX), which is synthesized endogenously from5-ALA via the heme pathway in the cell. READ MORE

  2. 2. A theoretical study of 5-Aminolevulinic acid and its esters : properties and lipid permeability

    Author : Edvin Erdtman; Leif Eriksson; Fahmi Himo; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biophysical chemistry; Biofysikalisk kemi; fysikalisk kemi; Physical Chemistry;

    Abstract : 5-aminolevulinic acid (5ALA) is a widely used prodrug in Photodynamic therapy (PDT). The target molecule in 5ALA-PDT is Protoporphyrin IX (PpIX), which is synthesized endogenously via the heme pathway in the cell. READ MORE

  3. 3. On the use of light for the characterization and treatment of malignant tumours

    Author : Claes af Klinteberg; Atomfysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Diffusion equation; Aminolevulinic acid; Protoporphyrin IX; Photodynamic therapy; Fluorescence spectroscopy; Fluorescence imaging; Laser-Doppler perfusion imaging; Atom- och molekylärfysik; Atomic and molecular physics; Multiple scattering; Tissue optics; Tissue optical properties; Fysicumarkivet A:1999:Klinteberg;

    Abstract : Some aspects on the use of light for tissue characterization and treatment of malignant tumours are discussed within this thesis. The work presented aims at improving optical techniques for tissue characterization, especially to detect malignant and pre-malignant lesions. READ MORE

  4. 4. Fluorescence Spectroscopy for Quantitative Demarcation of Glioblastoma Using 5-Aminolevulinic Acid

    Author : Neda Haj-Hosseini; Karin Wårdell; Göran Salerud; Peter E Andersen; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Abstract : Total resection of glioblastoma, the highly malignant brain tumor, is difficult to accomplish due to its diffuse growth and similarity to the surrounding brain tissue. A total resection is proven to increase patient survival. READ MORE

  5. 5. Photodynamic therapy and diagnosis of skin cancer : an investigation of photobleaching and technique optimisation

    Author : Marica B Ericson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; photodynamic therapy; oxygen dependence; flourescence imaging; photobleaching; delta-aminolevulinic acid; protoporphyrin IX; photodynamic diagnosis; basal cell carcinoma;

    Abstract : .... READ MORE