Search for dissertations about: "Amplified"
Showing result 1 - 5 of 350 swedish dissertations containing the word Amplified.
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1. Detection and Sequencing of Amplified Single Molecules
Abstract : Improved analytical methods provide new opportunities for both biological research and medical applications. This thesis describes several novel molecular techniques for nucleic acid and protein analysis based on detection or sequencing of amplified single molecules (ASMs). READ MORE
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2. MicroRNAs in HER2-Amplified Breast Cancer
Abstract : Background: Breast cancer is the most common female malignancy and the leading cause of cancer-related deaths worldwide. Targeted therapy against the main biomarkers estrogen receptor alpha (ER) and human epidermal growth factor receptor 2 (HER2/ERBB2) have greatly improved mortality rates, but ab initio or acquired therapy resistance is common. READ MORE
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3. Molecular Diagnostics Using Volume-Amplified Magnetic Nanobeads : Towards the Development of a Novel Biosensor System
Abstract : Micro- or nanometer sized magnetic particles (beads) currently have a vast range of life science applications in, for example, bioseparation techniques, cancer therapy, development of contrast agents and biosensing techniques. In the latter field, magnetic beads offer several unique advantages, including minimal background signals, physical and chemical stability and low manufacturing costs. READ MORE
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4. Detection of Biomolecules Using Volume-Amplified Magnetic Nanobeads
Abstract : This thesis describes a new approach to biomolecular analysis, called the volume-amplified magnetic nanobead detection assay (VAM-DNA). It is a sensitive, specific magnetic bioassay that offers a potential platform for the development of low-cost, easy-to-use diagnostic devices. READ MORE
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5. Nonlinearity mitigation in phase-sensitively amplified optical transmission links
Abstract : The fundamental limitations in fiber-optic communication are caused by optical amplifier noise and the nonlinear response of the optical fibers. The quantum-limited noise figure of erbium-doped fiber amplifier (EDFA) or any phase-insensitive amplifier is 3 dB. READ MORE