Search for dissertations about: "Anca Irinel Catrina"

Found 2 swedish dissertations containing the words Anca Irinel Catrina.

2. 1. Studies of molecular mechanisms of action of TNF antagonists in rheumatoid arthritis

   Author : Anca Irinel Catrina; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Rheumatoid arthritis; TNF antagonists; cytokines; macrophages; matrix metalloproteinases; osteoprotegerin; RANKL; apoptosis;

   Abstract : Rheumatoid arthritis (RA) is a common chronic inflammatory disease characterized by progressive bone destruction that leads to joint deformity and physical disability. Even though several therapeutic drugs are available, none have emerged as an ideal RA treatment that delays joint destruction and halts disease progression. READ MORE

4. 2. Presence of immunological markers preceding the onset of rheumatoid arthritis

   Author : Mikael Brink; Solbritt Rantapää Dahlqvist; Anca Irinel Catrina; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoantibodies; rheumatoid arthritis; anti citrullinated protein antibodies; pre-symptomatic individual; immunologi; Immunology; reumatologi; rheumatology;

   Abstract : Rheumatoid arthritis (RA) is a chronic inflammatory disease with an unknown aetiology characterized by joint destruction. Both genetic and environmental factors contribute to the disease development with HLA-DRB1* alleles and smoking identified as most important. READ MORE