Search for dissertations about: "Anders Blomberg"

Showing result 6 - 10 of 16 swedish dissertations containing the words Anders Blomberg.

  1. 6. Ozone and diesel exhaust : airway signaling, inflammation and pollutant interactions

    Author : Jenny Bosson; Anders Blomberg; Thomas Sandström; Ellinor Ädelroth; John Balmes; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; air pollution; ozone; diesel exhaust; airway inflammation; asthma; immunohistochemistry; Lung diseases; Lungsjukdomar; lungmedicin; Lung Medicine;

    Abstract : It is well established that air pollution has detrimental effects on both human health as well as the environment. Exposure to ozone and particulate matter pollution, is associated with an increase in cardiopulmonary mortality and morbidity. Asthmatics, elderly and children have been indicated as especially sensitive groups. READ MORE

  2. 7. Real-time breath gas analysis of carbon monoxide : laser-based detection and pulmonary gas exchange modeling

    Author : Ramin Ghorbani; Florian M. Schmidt; Anders Blomberg; Christoffer Boman; Staffan Schedin; Jonathan Beauchamp; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; carbon monoxide CO ; pulmonary gas exchange; computational modeling; real-time breath gas analysis; single-exhalation profile; laser absorption spectroscopy; nonlinear least-squares fitting; breath sampling; baseline level; diurnal variation; healthy population; exposure study; fysik; Physics; Physiology; fysiologi;

    Abstract : Breath gas analysis is a promising approach for non-invasive medical diagnostics and physiological monitoring. Real-time, breath-cycle resolved biomarker detection facilitates data interpretation and has the potential to improve the diagnostic value of breath tests as exhalation profiles carry spatiotemporal information about biomarker origin and gas exchange in the respiratory tract. READ MORE

  3. 8. Studies of Intracellular Transport and Anticancer Drug Action by Functional Genomics in Yeast

    Author : Marie Gustavsson; Hans Ronne; Anders Blomberg; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; 5-fluorouracil; tRNA modifications; Saccharomyces cerevisiae; carbamoyl phosphate synthase; V-ATPase; Functional genomics; Funktionsgenomik;

    Abstract : This thesis describes the use of functional genomics screens in yeast to study anticancer drug action and intracellular transport. The yeast Saccharomyces cerevisiae provides a particularly useful model system for global drug screens, due to the availability of knockout mutants for all yeast genes. READ MORE

  4. 9. Proteolytic imbalance in COPD : epidemiological and clinical aspects

    Author : Robert Linder; Anders Blomberg; Anne Lindberg; Annelie F. Behndig; Arne Egesten; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Matrix metalloproteinases; MMP-9; MMP-12; lung function decline; epidemiology; COPD; OLIN; KOLIN; medicin; Medicine;

    Abstract : Background: The complete pathologic mechanism behind the development of chronic obstructive pulmonary disease (COPD) remains unclear, but several risk factors have been identified, of which smoking is the most common. Proteolytic imbalance contributes to lung tissue degradation and is related to both smoking and COPD symptoms. READ MORE

  5. 10. Cardiovascular effects of diesel exhaust : mechanistic and interventional studies

    Author : Magnus Lundbäck; Anders Blomberg; Benoit Nemery; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; air pollution; diesel exhaust; nitrogen dioxide; endothelin-1; cardiovascular effects; exhaust particle trap; Lung diseases; Lungsjukdomar; lungmedicin; Lung Medicine;

    Abstract : Background: Air pollution is associated with negative health effects. Exposure to combustion-derived particulate matter (PM) air pollution has been related to increased incidence of cardiovascular and respiratory morbidity and mortality, specifically in susceptible populations. Ambient particles, with a diameter of less than 2. READ MORE