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Showing result 1 - 5 of 6 swedish dissertations matching the above criteria.

2. 1. Protein Engineering of Candida antarctica Lipase A : Enhancing Enzyme Properties by Evolutionary and Semi-Rational Methods

   Author : Anders G. Sandström; Jan-Erling Bäckvall; Uwe T. Bornscheuer; Stockholms universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; lipase; protein engineering; directed evolution; kinetic resolution; structural biology; Enzyme engineering; Enzymteknik; organisk kemi; Organic Chemistry;

   Abstract : Enzymes are gaining increasing importance as catalysts for selective transformations in organic synthetic chemistry. The engineering and design of enzymes is a developing, growing research field that is employed in biocatalysis. READ MORE

4. 2. Activation of epithelial signal transduction pathways, cytokine production and airway inflammation following diesel exhaust exposure

   Author : Jamshid Pourazar; Thomas Sandström; Anders Blomberg; Anders Lindén; Umeå universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : Adverse health effects of ambient air pollution are well recognised and include increased morbidity and mortality in respiratory and cardiovascular diseases. Diesel engines are major contributors to ambient particulate matter pollution and diesel particles have been shown to have strong toxicological and oxidative properties. READ MORE

5. 3. Epidemiology of asthma in primary school children

   Author : Anders Bjerg Bäcklund; Eva Rönmark; Bo Lundbäck; Thomas Sandström; Giovanni Viegi; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asthma; wheeze; child; allergic sensitisation; prevalence; remission; risk factor; trend; Lung diseases; Lungsjukdomar;

   Abstract : Background: Childhood asthma has increased worldwide, although recent studies report a prevalence plateau in some western countries.Aims: To investigate the prevalence of asthma and the associated risk factor patterns from ages 7-8 to 11-12 with special emphasis on the hereditary component, and further to study prevalence trends at age 7-8 from 1996 to 2006 and the possible determinants of these trends. READ MORE

6. 4. Pathogenesis and treatment of chemical-induced lung injury

   Author : Elisabeth Wigenstam; Anders Bucht; Thomas Sandström; Kjell Larsson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chemical-induced lung injury; dexamethasone; melphalan; vitamin E; respiratory mechanics; lungmedicin; Lung Medicine;

   Abstract : Inhalation of chemical substances can cause irritation to airways and in high doses acute airway injury. When mice are exposed to the alkylating nitrogen mustard analogue melphalan they develop an acute airway inflammation with a rapid influx of neutrophils to the lungs. READ MORE

7. 5. Activation of lung epithelial cells by group 2 mite allergens

   Author : Camilla Österlund; Anders Bucht; Thomas Sandström; Jan Wahlström; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; group 2 mite allergens; Der p 2; Der f 2; Eur m 2; Lep d 2; airway epithelium; lungmedicin; Lung Medicine;

   Abstract : Throughout many parts of the world house dust mites (HDM) are considered as a major source of indoor aeroallergens and they are powerful inducers of allergic diseases. Proteolytic HDM allergens are recognised as being able to directly activate respiratory epithelial cells and thereby actively participate in innate immune responses. READ MORE