Search for dissertations about: "Andis Slaitas"

Found 1 swedish dissertation containing the words Andis Slaitas.

2. 1. Development of a new PNA analogue as a potential antisense drug and tool for life-science studies

   Author : Andis Slaitas; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The work described in this thesis focuses on applying synthetic organic chemistry methods (supported by modem synthesizers and analytical techniques) for the preparation of peptides and modified nucleic acids in order to affect certain properties in these biomolecules, which can lead to their application as drugs and/or tools for life sciences studies. The first part of the thesis reports the design and synthesis of a novel pyrrolidine-based peptide nucleic acid (PNA). READ MORE