Search for dissertations about: "Anesthetics"

Showing result 1 - 5 of 43 swedish dissertations containing the word Anesthetics.

  2. 1. Molecular Dynamics Investigations of Structure and Dynamics of Lipid Bilayers and Associated Anesthetics

    Author : Carl-Johan Högberg; Alexander Lyubartsev; Lennart Nilsson; Stockholms universitet; []
    Keywords : DMPC; Molecular dynamics simulations; Anesthetics; Lidocaine; Physical Chemistry; fysikalisk kemi;

    Abstract : Detailed understanding of lipid bilayers are of tremendous importance due to their role in many biological processes. This Thesis focuses on structural and dynamical properties of lipid bilayers and their interactions with locally acting anesthetics, studied by Molecular Dynamics simulations. READ MORE

  4. 2. Studies on local anesthetics : Xylocaine : a new synthetic drug

    Author : Nils Löfgren; Stockholms högskola; []
    Keywords : ;

    Abstract : .... READ MORE

  5. 3. Formulations, Release and Skin Penetration of Topical Anesthetics

    Author : Katayoun Welin-Berger; Brian W. Barry; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; galenisk farmaci; Pharmaceutics;

    Abstract : This thesis describes certain critical aspects of the development of semisolid topical anesthetic formulations requiring a fast onset of action. Furthermore, local anesthetics were investigated regarding their phase interaction with membrane lipids. READ MORE

  6. 4. Solid-State NMR Characterization of Lipid Membranes

    Author : Vasco Castro; Arnold Maliniak; Göran Lindblom; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Solid-State NMR; Membranes; Lipids; Glycolipids; Local Anesthetics; Hydration; Physical chemistry; Fysikalisk kemi; Physical Chemistry; fysikalisk kemi;

    Abstract : This thesis deals with the study of lipid bilayer systems by solid-state nuclear magnetic resonance. Two-dimensional 1H-13C separated local field experiments under magic-angle spinning were employed to investigate structural and dynamical modifications of cell membranes, resulting from the addition of compounds with some biological relevance. READ MORE

  7. 5. A multivariate approach to QSAR

    Author : Sven Hellberg; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; QSAR; beta-adrenergic agents; haloalkanes; halogenated anesthetics; peptides; fractional factorial design; multivariate data analysis; principal components PC ; partial least squares PLS ;

    Abstract : Quantitative structure-activity relationships (OSAR) constitute empirical analogy models connecting chemical structure and biological activity. The analogy approach to QSAR assume that the factors important in the biological system also are contained in chemical model systems.The development of a QSAR can be divided into subproblems:1. READ MORE