Search for dissertations about: "Aneuploidy"

Showing result 11 - 15 of 63 swedish dissertations containing the word Aneuploidy.

  2. 11. p53 and neoplastic progression in Barrett's esophagus

    Author : Stig Ramel; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Barrett s esophagus; neoplastic progression; flow cytometry; p53 gene; p53protein; 17p allelic loss; p53 mutations; S phase fractions; aneuploidy; SV 40 large T antigen; elastase-SV 40 T antigen transgenic mice.;

    Abstract : Barrett's esophagus is a condition in which the normal squamous epithelium is replaced by columnar epithelium as a response to acid reflux. It develops as a complication in 10-20% of patients with gastroesophageal reflux disease. READ MORE

  4. 12. Ulcerative colitis and cancer with special reference to the increased colorectal cancer risk

    Author : Per Karlén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Ulcerative colitis; cancer; inflammatory bowel disease; colorectal cancer; colonoscopic surveillance; epidemiology; flow cytometry DNA; Sialyl-Tn antigen; primary sclerosing cholangitis; hepatobiliary tract; case-control studies;

    Abstract : The association between ulcerative colitis (UC) and cancer in a defined geographical region in Sweden was analyzed. UC patients have an increased overall risk of cancer of 40%, mainly due not only to the well-known increased risk of colorectal cancer (CRC) but also to the risk of hepatobiliary cancer associated with primary sclerosing cholangitis (PSC). READ MORE

  5. 13. Long-term survival and prognostic factors in endometrial cancer - a populationbased cohort study

    Author : Teresia Svanvik; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endometrial cancer; relative survival; DNA ploidy; s-phase fraction; p53; socioeconomic inequality; early detection;

    Abstract : Aims: The over-all aims of this thesis were to evaluate the associations between prognostic factors and excess mortality rate, between socioeconomic and immigrant status and incidence rate, in endometrioid (EEC) and non-endometrioid (NEC) endometrial carcinoma. Material and methods: Study I-III were retrospective population-based cohort studies including women resident in a defined geographical area, with endometrial carcinoma. READ MORE

  6. 14. The mouse oocyte as a model in reproductive toxicology studies

    Author : Jinwen Zhang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : It is suspected that certain chemicals may cause alterations in female reproduction, including ovarian failure and birth defects. Sub-fecundity, infertility, pregnancy loss, fetal growth retardation, and birth defects are consequences proposed to occur. READ MORE

  7. 15. Small breast cancers : Diagnosis, prognostic factors and clinical outcome in a screening population

    Author : Lars-Gunnar Arnesson; Karl von Smitten; Linköpings universitet; []
    Keywords : Breast neoplasm; diagnostic; treatment; pathology; MEDICINE; MEDICIN;

    Abstract : Breast cancer ≤ 10 mm together with ductal in situ cancer of the breast (DCIS) today constitute more than 40% of screening detected breast malignancies. Prognostic factors, diagnosis and clinical outcome for invasive breast cancers ≤ 10 mm and local recurrence in DCIS were evaluated. READ MORE