Search for dissertations about: "Animal Models"
Showing result 1 - 5 of 757 swedish dissertations containing the words Animal Models.
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1. Novel Treatment Modalities for High-Risk Neuroblastoma : Studies in Animal Models
Abstract : Neuroblastoma, the most common extracranial solid tumor of childhood, is a heterogeneous tumor. In some patients, the tumor can go into spontaneous regression and disappear whereas other patients have rapidly growing tumors with a poor prognosis. READ MORE
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2. Assessment of eosinophil degranulation in allergic diseases and experimental models
Abstract : In allergic disorders, the eosinophilic granulocytes migrate to affected tissues and release granule proteins with cytotoxic, immunoregulatory, and remodeling-promoting properties. Given that degranulation is reflected by a loss in eosinophil granule density of living cells, or by cell membrane rupture and release of intact granules, these morphological changes may represent a biomarker of the allergic disease. READ MORE
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3. Hantaviruses : animal models, immunology and pathogenesis
Abstract : Hantaviruses cause two serious and often fatal human zoonotic diseases: hemorrhagic fever with renal syndrome (HFRS) in Eurasia, and hantavirus cardiopulmonary syndrome (HCPS) in the Americas. Hantaviruses are rodent-borne and are transmitted to humans via inhalation of contaminated rodent excreta. READ MORE
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4. Genetic Heteroscedasticity for Domestic Animal Traits
Abstract : Animal traits differ not only in mean, but also in variation around the mean. For instance, one sire’s daughter group may be very homogeneous, while another sire’s daughters are much more heterogeneous in performance. The difference in residual variance can partially be explained by genetic differences. READ MORE
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5. From disease to genes in animal models of rheumatoid arthritis and multiple sclerosis
Abstract : Rheumatoid arthritis (RA) and multiple sclerosis (MS) are complex inflammatory autoimmune diseases. The aetiology is largely unknown but the risk of developing disease is dependent on both genetic and environmental factors. READ MORE