Search for dissertations about: "Animal model"
Showing result 6 - 10 of 1013 swedish dissertations containing the words Animal model.
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6. Ontogeny and Population Biology of a Sex-Limited Colour Polymorphism
Abstract : This study has involved investigation of number of populations of the damselfly Ischnura elegans over several years, looking at frequency changes over time, morphological differences between the sexes and the morphs, differences in growth rate and development time, differences in fecundity between the morphs, and genetic differentiation between populations. I. READ MORE
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7. Haemophilus influenzae-induced acute otitis media. Aspects of virulence and protection in an animal model
Abstract : Acute otitis media (AOM) is the most common illness diagnosed during early childhood. One of the major etiologic agents is Haemophilus influenzae. Apart from AOM, this organism can cause a broad range of infectious diseases such as meningitis, epiglottitis, arthritis, and pneumonia. Despite the importance of H. READ MORE
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8. Genetic Studies of Rheumatoid Arthritis using Animal Models
Abstract : Predisposition to autoimmune diseases such as, rheumatoid arthritis, diabetes, and multiple sclerosis, is caused by the effect of multiple genes and a strong influence from the environment. In this study, I have investigated genetic factors that confer susceptibility to rheumatoid arthritis in a rat model. READ MORE
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9. Unraveling the genetics of lymphocytic thyroiditis using the dog as a model
Abstract : The domestic dog, with its unique genetic structure formed by domestication and recent breed creation, has been proven to be an excellent model for mapping disease genes. In this thesis, we use the dog as a model to investigate the prevalence and genetic background of canine lymphocytic thyroiditis (CLT), one of the most common immune related diseases in dogs. READ MORE
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10. Beta Cell Function: from Human Genetics to Animal Models
Abstract : Beta cell function is an important factor in the development of both Type 1 (T1D) and Type 2 (T2D) diabetes mellitus. T1D is characterized by a primary defect in insulin secretion due to the immune-mediated beta cell destruction, however, the more common T2D beside insulin resistance also include impaired beta cell function as a consequence to abnormal glucose homeostasis. READ MORE