Search for dissertations about: "Animal models in research"

Showing result 1 - 5 of 209 swedish dissertations containing the words Animal models in research.

  2. 1. The Role of Microvascular Pericytes in the Generation of Pro-fibrotic Connective Tissue Cells : Investigations in vitro and in Reactive Tissues in vivo

    Author : Jakob Karén; Christian Sundberg; Gunilla Westergren-Thorsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pericyte fibroblast differentiation fibrosis; Biochemistry; Biokemi; Microbiology; Mikrobiologi; Cell biology; Cellbiologi; Medical Biochemistry; Medicinsk biokemi; Cellforskning; Cell Research; Mikrobiologi; Microbiology;

    Abstract : Pericytes are cells of mesenchymal origin located on the abluminal side, juxtapositioned to the endothelial cells in capillaries, venules and small arterioles. They are important for maintaining vessel integrity in resting tissues as well as the formation and stabilization of new vessels. READ MORE

  4. 2. Metabolic variation in autoimmune diseases

    Author : Rasmus Kirkegaard Madsen; Johan Trygg; Thomas Moritz; Torbjörn Lundstedt; Matej Oresic; Umeå universitet; []
    Keywords : Rheumatoid Arthritis; Diabetes Mellitus type 1; Metabolic Profiling; Metabolomics; Chemometrics; Multivariate Data Analysis; Mass Spectrometry; biologisk kemi; biological chemistry;

    Abstract : The human being and other animals contain immensely complex biochemical processes that govern their function on a cellular level. It is estimated that several thousand small molecules (metabolites) are produced by various biochemical pathways in humans. READ MORE

  5. 3. Diabetes in 3D : β-cell mass assessments in disease models & evaluation of SPECT based imaging

    Author : Saba Parween; Ulf Ahlgren; Helena Edlund; Eckhard Lammert; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Optical projection tomography; Diabetes; β-cell mass; disease etiology; 3D imaging; radiotracers; Single photon emission computed tomography; molekylär medicin genetik och patologi ; molecular medicine  genetics and pathology ;

    Abstract : Diabetes is a rapidly growing disease with 415 million affected adults worldwide. The pancreatic endocrine cells, most importantly the insulin producing β-cells, play an important role in regulating blood glucose homeostasis. READ MORE

  6. 4. Proteomics in biomarker research : Insights into the effects of aging and environment on biological systems

    Author : Hanna Amelina; Susana Cristobal; Jean-Charles Sanchez; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; proteomics; biomarker; peroxisomes; 2-dimensional gel electrophoresis 2-DE ; mass spectrometry MS ; aging; marine pollution; Biochemistry; Biokemi; Environmental toxicology; Miljötoxikologi; Cell and molecular biology; Cell- och molekylärbiologi; Biochemistry; biokemi;

    Abstract : Proteomics is the global analysis of proteins that covers a broad range of technologies aimed at determining the identity and quantity of proteins expressed in the cell, their three-dimensional structure and interaction partners. In contrast to genome, proteome reflects more accurately on the dynamic state of the cell, tissue, or an organism. READ MORE

  7. 5. Surgery and Ischemia in Uterus Transplantation. Studies in various experimental models

    Author : Caiza Wranning; Göteborgs universitet; []
    Keywords : animal models; cold ischemia-reperfusion injury; inflammation; transplantation; uterus;

    Abstract : The use of transplantation to enhance quality of life is a growing clinical field that also includes transplantation of reproductive organs. Transplantation of the uterus has been suggested as future method to treat uterus factor infertility. READ MORE