Search for dissertations about: "Anita M. Persson"

Found 1 swedish dissertation containing the words Anita M. Persson.

2. 1. Evaluation of a Miniaturized Rotating Disk Apparatus for In Vitro Dissolution Rate Measurements in Aqueous Media : Correlation of In Vitro Dissolution Rate with Apparent Solubility

   Author : Anita M. Persson; Curt Pettersson; Anders Sokolowski; Anders Karlsson; Alex Avdeef; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; analytical methods; HPLC high-performance liquid chromatography ; miniaturization; in vitro dissolution rate; apparent solubility; physicochemical properties; dissolution media; correlation study; chemometrics; Pharmaceutical chemistry; Farmaceutisk kemi; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

   Abstract : The general aim of this thesis was to evaluate a newly designed and constructed miniaturized rotating disk apparatus for in vitro dissolution rate measurements of different drug substances from all of the classes in the Biopharmaceutical Classification System (BCS). The new equipment is based on a low volume flow-through cell of Plexiglas, a gold plated magnetic bar and a special designed press. READ MORE