Search for dissertations about: "Anna Asp"

Showing result 6 - 10 of 12 swedish dissertations containing the words Anna Asp.

  1. 6. Structural and Functional Studies of Chagasin, a Parasite Protease Inhibitor

    Author : Anna Ljunggren; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The cysteine proteases are enzymes found in every kingdom of life. Clan CA is the largest of the cysteine protease clans, with members all displaying a Cys/His/Asn(Asp) catalytic triad responsible for hydrolysing the peptide bond within the substrate. READ MORE

  2. 7. Studies on global regulators involved in virulence gene expression in Staphylococcus aureus

    Author : Anna Kanth; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Staphylococcus aureus is a leading cause of skin, soft tissue, respiratory and endovascular diseases. Staphylococcal pathogenicity depends on the coordinated action of at least 40 different virulence factors, including cytolytic toxins (hla, hlb, luk) enterotoxins (ent), several proteases (ssp, aur, scp) and a large number of cell wall-associated proteins, such as protein A (spa), and fibronectin binding protein (FnBPs). READ MORE

  3. 8. Pharmacological evaluation of the NO/cGMP signalling system

    Author : Anna Asplund Persson; Karl-Erik Andersson; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Platelet activation and inhibition are tightly balanced processes, regulated by various endogenous molecules. In this regard, the endothelium plays a key role in mediating inhibition of platelets by releasing nitric oxide (NO) and cAMP-elevating prostaglandins. READ MORE

  4. 9. Studies on Cervical Artificial Disc Replacement

    Author : Catarina Marques; Claes Olerud; Anna MacDowall; Martin Skeppholm; Adrian Elmi Terander; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cervical radiculopathy; artificial disc replacement; Orthopaedics; Ortopedi; Neurokirurgi; Neurosurgery;

    Abstract : Artificial disc replacement (ADR) was developed as an alternative to anterior fusion after decompression for cervical degenerative radiculopathy. By preserving motion, it was expected to prevent acceleration of adjacent segment pathology (ASP) associated with fusion, and lead to better clinical outcomes. READ MORE

  5. 10. Characterization of Diagnostic Tools and Potential Treatments for Alzheimer’s Disease : PET ligands and BACE1 inhibitors

    Author : Fredrik Jeppsson; Anna-Lena Ström; Kerstin Iverfeldt; Samuel Svensson; Martin Hallbeck; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Alzheimer’s disease; Diagnostics; Treatment; PET ligand; BACE1; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Alzheimer’s disease (AD) is a very complex disorder and the most common form of dementia. The two pathological hallmarks of AD are extracellular amyloid-β (Aβ) plaques in cerebral cortex, and intraneuronal neurofibrillary tangles. READ MORE