Search for dissertations about: "Anti-inflammatory"

Showing result 1 - 5 of 487 swedish dissertations containing the word Anti-inflammatory.

  2. 1. Uridine, 4-thiouridine and isomaltitol in an asthma-like model : Anti-inflammatory and modulating effects

    Author : Chamilly Evaldsson; Srinivas Uppugunduri; Margareta Linden; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Uridine; asthma; 4-thiouridine; isomaltitol; isomalt; inflammation; eosinophilia; Sephadex; animal model; rat; Pharmaceutical pharmacology; Farmaceutisk farmakologi; MEDICINE; MEDICIN; Lung diseases; Lungsjukdomar;

    Abstract : In chronic inflammatory diseases like asthma or rheumatoid arthritis, erroneous and exaggerated accumulation of leukocytes in a tissue inadvertently causes the body harm. Several efficient anti-inflammatory drugs exist, for example corticosteroids and cyclo-oxygenase inhibitors. READ MORE

  4. 2. Molecular mechanisms of glucocorticoids : anti-inflammatory implications

    Author : Krishan Johansson-Haque; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Glucocorticoids (GCs) play important roles in many biological processes including inflammatory responses. The study of this process has involved investigations of cross-talk abilities by GC receptor (GR) with cellular signaling pathways that have been associated with inflammatory disorders or implicated as contributory for the adverse effects observed with GC therapy. READ MORE

  5. 3. Non-Steroidal Anti-Inflammatory Drugs in Cyclooxygenases 1 and 2 : Binding modes and mechanisms from computational methods and free energy calculations

    Author : Yasmin Shamsudin Khan; Johan Åqvist; Hugo Gutiérrez de Terán; Xavier Barril; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; molecular dynamics simulations; binding free energy; molecular docking; cyclooxygenase; non-steroidal anti-inflammatory drugs; free energy perturbation; potentials of mean force;

    Abstract : Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly used classes of drugs. They target the cyclooxygenases (COX) 1 and 2 to reduce the physiological responses of pain, fever, and inflammation. Due to their role in inducing angiogenesis, COX proteins have also been identified as targets in cancer therapies. READ MORE

  6. 4. Antimicrobial and anti-inflammatory agents in experimental gingivitis

    Author : Satoshi Sekino; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The main objectives of the present series of experiment was to evaluate i) the microbial changes that occurred in plaque during de novo plaque formation, ii) the influence of the number of bacteria in saliva on de novo plaque formation, iii) the effect of a chlorhexidine regimen on the recolonization of bacterial species in plaque and saliva, iv) the effect of systemic administration of ibuprofen on gingivitis development and de novo plaque formation and v) the effect of a mouthrinse containing Listerine® on gingivitis development and de novo plaque formation.Subjects with no signs of periodontal disease were recruited. READ MORE

  7. 5. Pro- and anti-inflammatory actions in coronary artery disease : with focus on CD56+ T cells and Annexin A1

    Author : Ida Bergström; Lena Jonasson; Eva Särndahl; Jan Ernerudh; Johan Frostegård; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : ¨The atherosclerotic process is considered to be driven by an imbalance between proand anti-inflammatory actions. Still, the inflammatory state in patients with coronary artery disease (CAD) remains to be clarified. READ MORE