Search for dissertations about: "Antibiotic consumption"

Showing result 21 - 25 of 32 swedish dissertations containing the words Antibiotic consumption.

  2. 21. Role of antimicrobial peptides in tuberculosis and respiratory tract infections : clinical and mechanistic studies

    Author : Rokeya Sultana Rekha; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Antimicrobial peptides (AMPs) are effector molecules of the innate immune system in multicellular organisms. They are mainly expressed in epithelial cells and immune cells, providing the first line of defense against a wide range of pathogens. READ MORE

  4. 22. Novel tools for the study and diagnosis of bacterial infections : exploring the intersection of microbiology and microfabrication

    Author : Charalampos Antypas; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The alarming increase in antibiotic resistance calls for new approaches to study and diagnose bacterial infections. In my thesis, I worked at the intersection of microbiology, microfabrication, and optical probes to develop novel diagnostic and screening assays for microbiology and elucidate bacterial pathogenesis in urinary tract infections (UTI). READ MORE

  5. 23. Complications after total hip arthroplasty : register-based studies on surgical approach and infections

    Author : Viktor Lindgren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: The often excellent outcome of total hip arthroplasty (THA) is sometimes compromised by prosthesis related complications. There is an ongoing debate regarding the effect of surgical approach on prosthesis related complications and patient reported outcome. READ MORE

  6. 24. Oxygen delivery and mitochondrial dysfunction as assessed by microdialysis during interventions in experimental sepsis

    Author : Magnus von Seth; Lipscey Miklós; Jan Sjölin; Mats Eriksson; Jukka Takala; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; animal models; microdialysis; endotoxin; Escherichia coli; tigecycline; doxycycline; albumins; capillary leak syndrome; lactic acid; oxygen delivery; multiple organ failure; mitochondria; tumor necrosis factor alpha; interleukin-6; cyanides; ouabain; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Abstract : Early administration of broad-spectrum antibiotics is the first goal in sepsis treatment. Besides from bacteriostatic/bactericidal effects, some antibiotics may also modify the host´s response to infection. The novel antibiotic tigecycline may exert such properties; however, this property has not been evaluated in large-animal trials. READ MORE

  7. 25. Mechanisms and Inhibition of EF-G-dependent Translocation and Recycling of the Bacterial Ribosome

    Author : Anneli Borg; Måns Ehrenberg; Ruben Gonzalez; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein synthesis; Elongation factor G; Translocation; Ribosome recycling; Fusidic acid; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : The GTPase elongation factor G (EF-G) is an important player in the complex process of protein synthesis by bacterial ribosomes. Although extensively studied much remains to be learned about this fascinating protein. READ MORE