Search for dissertations about: "Antibiotics"

Showing result 21 - 25 of 544 swedish dissertations containing the word Antibiotics.

  2. 21. Fluorimetric Bioprobe Based on DNA-dye Intercalation - Application in Enviromental and Clinical Monitoring

    Author : Yang Liu; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bioteknik; Biotechnology; Biokemisk teknik; Biochemical technology; Antibiotics; Toxic aromatic compounds; Doxorubicin; High throughput screening; Fluorimetric assay; DNA;

    Abstract : Nucleic acids have many unique structural features that offer reliable means of recognizing and monitoring many compounds of medical or environmental importance. In recent years, there has been an enormous increase in the use of nucleic acids as a tool to determine the chemical compounds of environmental and clinical interest and the major research activities in these areas have been directed towards the design of sequence-selective biosensors based on hybridization. READ MORE

  4. 22. Pharmacometric Models for Antibacterial Agents to Improve Dosing Strategies

    Author : Elisabet I Nielsen; Lena E Friberg; Otto Cars; Mats O Karlsson; Marie Sandström; Alan Forrest; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacometrics; pharmacokinetics; pharmacodynamics; modeling; NONMEM; antibiotics; in vitro; time-kill curve; PK PD indices; gentamicin; aminoglycosides; newborn infants; premature infants; cystatin C; Biopharmacy; Biofarmaci; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Abstract : Antibiotics are among the most commonly prescribed drugs. Although the majority of these drugs were developed several decades ago, optimal dosage (dose, dosing interval and treatment duration) have still not been well defined. READ MORE

  5. 23. Effects of pharmaceuticals on natural microbial communities: Tolerance development, mixture toxicity and synergistic interactions

    Author : Sara Brosché; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; antibiotics; pharmaceutical mixtures; microbial community ecotoxicology;

    Abstract : Due to our extensive use of pharmaceuticals, low concentrations (picomol-nanomol/L) end up in the aquatic environment. Antibiotics comprise a group of pharmaceuticals specifically designed to disrupt microbial biochemical processes, and might therefore in particular have detrimental effects on microbial communities in the environment. READ MORE

  6. 24. Defeating Disease : Lasting Effects of Public Health and Medical Breakthroughs between 1880 and 1945 on Health and Income in Sweden

    Author : Volha Lazuka; Centrum för ekonomisk demografi; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; public health; antibiotics; inflammation; early life; health; income; end of the 19th–20th century;

    Abstract : This thesis has the general aim of exploring the role of public health and medical interventions between 1880 and 1945, targeting infectious diseases, in health and income improvements in Sweden throughout the twentieth century. It applies methods of causal inference to longitudinal individual-level data from both local and national datasets combined with multisource archival data on the implementation of reforms. READ MORE

  7. 25. Tracking single molecules in uncharted territory : A single-molecule method to study kinetics in live bacteria

    Author : Javier Aguirre Rivera; Magnus Johansson; Dmitri N. Ermolenko; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; single-molecule; protein synthesis; fluorescence microscopy; antibiotics; aminoglycosides; macrolides; apramycin; gentamicin; paromomycin; S13; translation; bacteria; Molekylär biovetenskap; Molecular Life Sciences;

    Abstract : The synthesis of proteins, also known as translation, is a fundamental process in every living organism. The steps in the translation of genetic information to functional proteins have been meticulously studied, mostly using in vitro techniques, yielding a detailed model of their mechanisms. READ MORE