Search for dissertations about: "Antidepressant response"

Showing result 1 - 5 of 47 swedish dissertations containing the words Antidepressant response.

  1. 1. Adherence to Antidepressant Medication

    Author : Ann-Charlotte Åkerblad; Lisa Ekselius; Ingvar Krakau; Uppsala universitet; []
    Keywords : Psychiatry; adherence; depression; randomised controlled trial; intervention; therapeutic drug monitoring; personality; health status; health care utilisation; Psykiatri;

    Abstract : Non-adherence to medication is a major obstacle in the treatment of depression. The objectives of the present study were to explore the effect of two interventions aiming to increase antidepressant treatment adherence, and to examine long-term consequences and costs of depression in adherent and non-adherent primary care patients. READ MORE

  2. 2. Characterization of secretory mechanisms in lacrimal and salivary glands

    Author : Martin Dankis; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dry mouth; dry eyes; antidepressant; muscarinic; purinergic; salivary secretion; tear secretion; lacrimal gland; in vivo; primary culture; co-culture; acinar; myoepithelial;

    Abstract : Dry mouth and dry eyes are multifactorial morbidities that can lead to a severely reduced quality of life. Approximately 20% of the population suffers from ocular or oral dryness. READ MORE

  3. 3. P-glycoprotein and chiral antidepressant drugs : Pharmacokinetic, pharmacogenetic and toxicological aspects

    Author : Louise Karlsson; Fredrik C. Kugelberg; Finn Bengtsson; Johan Ahlner; Aleksander A. Mathé; Linköpings universitet; []
    Keywords : ;

    Abstract : The blood-brain barrier (BBB) is formed by the capillary endothelial cells, joined together by tight junctions, with transporter proteins. BBB acts to regulate the brain concentrations of substances including many drugs. READ MORE

  4. 4. On the efficacy and prescription of serotonin reuptake inhibitors

    Author : Alexander Lisinski; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antidepressants; antidepressive agents; major depressive disorder; selective serotonin reuptake inhibitor; serotonin and noradrenaline reuptake inhibitor; tricyclic antidepressant;

    Abstract : This thesis addresses several controversial issues regarding commonly used antidepressants, including selective serotonin reuptake inhibitors (SSRIs), serotonin and noradrenaline reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs). To this end, patient-level data from 28 placebo-controlled trials on SSRIs and 13 corresponding trials on the SNRI duloxetine, were requested and obtained. READ MORE

  5. 5. On the hypersensitivity syndrome induced by the selective serotonin reuptake inhibiting antidepressant Zimeldine : A clinical and experimental study

    Author : Bengt-O Bengtsson; Linköpings universitet; []
    Keywords : Zimeldine; Norzimeldine; Hypersensitivity syndrome; Serotonin reuptake inhibition; Genetic disposition; Lymphocyte transformation test; Experimental allergic neuritis; Immunopharmacology; MEDICINE; MEDICIN;

    Abstract : Zimeldine, the first selective neuronal serotonin (5-H1) reuptake inhibitor to be registered as an antidepressant was withdrawn from common use due to an acute flu-like adverse syndrome comprising fever, myalgia and/or arthralgia and signs of disturbed liver function. A few of these patients also developed a peripheral neuropathy, in the most serious form a Guillain-Barré syndrome (GBS). READ MORE