Search for dissertations about: "Antigen drift"

Found 2 swedish dissertations containing the words Antigen drift.

  1. 1. Influenza virus : protection and adaptation

    Author : Camilla Maria Mittelholzer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Human influenza A virus; DNA vaccine; Neutralisation test; Antigen drift;

    Abstract : Influenza is an acute respiratory disease caused by influenza type A and B viruses. Human influenza viruses may infect up to 15% of the total population during the seasonal epidemics, causing many cases of severe illness. Each year, approximately 350 million doses of influenza vaccine are produced for protection of those at risk of severe disease. READ MORE

  2. 2. Variable viral genes as genetic immunogens

    Author : Karl Ljungberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Influenza; hemagglutinin; HIV-1; gp160; DNA vaccine; genetic immunization; CpG; GM-CSF; pseudovirus.;

    Abstract : Influenza and HIV-1 are two highly variable viruses that cause extensive morbidity and mortality in many countries. The most cost-effective medical intervention against influenza is vaccination but this has to be repeated annually because of the low antigenicity of the vaccine. READ MORE