Search for dissertations about: "Antimicrobial agents"

Showing result 1 - 5 of 52 swedish dissertations containing the words Antimicrobial agents.

  1. 1. Antimicrobial peptides in the treatment of infectious and inflammatory conditions Preclinical studies of mechanism of action, efficacy, and safety

    University dissertation from Göteborgs universitet

    Author : Camilla Björn; Medicinteknik.; Göteborgs universitet.; Gothenburg University.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial peptides; AMPs; innate immunity; infection; inflammation; mechanism of action; efficacy; safety; antimicrobial resistance; antibiotic resistance; Antimicrobial peptides;

    Abstract : The rapid emergence of antibiotic-resistant microbes worldwide and the urgent need of new antimicrobial agents have stimulated interest in antimicrobial peptides (AMPs) as new therapeutics for treatment of infectious diseases. AMPs are present in all living species and constitute an important part of the innate immune system in multicellular organisms, including humans. READ MORE

  2. 2. Carbon monoxide and nitric oxide as antimicrobial agents : focus on ESBL-producing uropathogenic E.coli

    University dissertation from Örebro : Örebro university

    Author : Charlotte Sahlberg Bang; Örebro universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biofilm; carbon monoxide; CORM-2; DETA NO; extendedspectrum beta-lactamases; nitric oxide; urinary tract infection; uropathogenic Escherichia coli; Biomedicin; Biomedicine;

    Abstract : Urinary tract infections (UTI) are common in humans and most often caused by uropathogenic Escherichia coli (E. coli). Extended-spectrum beta-lactamase (ESBL)-producing E. coli are increasing worldwide and they are frequently multidrug-resistant with limited treatment options. READ MORE

  3. 3. Antimicrobial and anti-inflammatory agents in experimental gingivitis

    University dissertation from Göteborg : Göteborg University

    Author : Satoshi Sekino; Göteborgs universitet.; Gothenburg University.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The main objectives of the present series of experiment was to evaluate i) the microbial changes that occurred in plaque during de novo plaque formation, ii) the influence of the number of bacteria in saliva on de novo plaque formation, iii) the effect of a chlorhexidine regimen on the recolonization of bacterial species in plaque and saliva, iv) the effect of systemic administration of ibuprofen on gingivitis development and de novo plaque formation and v) the effect of a mouthrinse containing Listerine® on gingivitis development and de novo plaque formation.<br/>Subjects with no signs of periodontal disease were recruited. READ MORE

  4. 4. Mechanisms and Biological Costs of Bacterial Resistance to Antimicrobial Peptides

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Hava Lofton Tomenius; Uppsala universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial peptides; antibiotic resistance; fitness cost; Salmonella Typhimurium; Staphylococcus aureus; bile; serum; pH response; growth rate; mice; phoP; pmrB; waaY; LPS; LL-37; defensins; membrane potential; Mikrobiologi; Microbiology;

    Abstract : The global increasing problem of antibiotic resistance necessarily drives the pursuit and discovery of new antimicrobial agents. Antimicrobial peptides (AMPs) initially seemed like promising new drug candidates. Already members of the innate immune system, it was assumed that they would be bioactive and non-toxic. READ MORE

  5. 5. Defence capabilities of human intestinal epithelial cells

    University dissertation from Umeå : Umeå universitet

    Author : Anna Fahlgren; Umeå universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; intestine; mucosa; epithelium; antimicrobial; defensins; glycocalyx; ulcerative colitis; Crohn´s disease; celiac disease; Immunologi; MEDICINE Microbiology; immunology; infectious diseases Immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi; immunologi; Immunology;

    Abstract : The epithelial cells lining the intestinal mucosa separate the underlying tissue from components of the intestinal lumen. Innate immunity mediated by intestinal epithelial cells (IECs) provides rapid protective functions against microorganisms. Innate immunity also participates in orchestrating adaptive immunity. READ MORE